| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-38356 |
Darovasertib
|
1874276-76-2 |
Darovasertib (LXS 196, IDE 196) is a selectve, oral small molecule protein kinase C (PKC) inhibitor, demonstrating promising efficacy in metastatic uveal melanoma (MUM) combined with Crizotinib. |
| PC-35337 |
ζ-Stat
|
3316-02-7 |
ζ-Stat (1,3,6-Naphthalenetrisulfonic acid) is a novel PKC-zeta (PKC-ζ) specific inhibitor with IC50 of 5 uM, showed only 13%
inhibition on PKC-I at 20 uM. |
| PC-63489 |
PKCiota-IN-49
|
2230055-52-2 |
PKCiota-IN-49 is a potent and selective inhibitor of Protein Kinase C iota (PKC-ι) with IC50 of 2.8 nM, >20-fold selectivity over PKC-α (IC50=71 nM) and PKC-β (IC50=350 nM). |
| PC-62375 |
BJE6-106
|
1564249-38-2 |
BJE6-106 (B106) is a potent, selective PKCδ inhibitor with IC50 of 50 nM, displays excellent selectivity over classical PKC isozymes (a 1,000-fold PKCδ selectivity over PKCα). |
| PC-60994 |
AS2521780
|
1214726-89-2 |
AS2521780 is a potent, selective, orally bioavailable PKCθ inhibitor that inhibits combinant human PKCθ enzyme with IC50 of 0.48 nM, >30-fold higher than other PKC isoforms. |
| PC-38836 |
Z640
|
353793-07-4 |
Z640 is a novel non-selective atypical PKC (aPKC) agonist, increases PKCζ and PKCι kinase activity with EC50 of 1.09 and 3.47 µM in vitro kinase activity assays, respectively. |
| PC-73059 |
NP627
|
412962-32-4 |
NP627 (NP-627) is a specific small-molecule inhibitor of protein kinase C deltaI (PKCδI) with Kd of 1 nM. |
