PKN2-IN-1

Chemical Structure : PKN2-IN-1

Catalog No.: PC-27816Not For Human Use, Lab Use Only.

PKN2-IN-1 (Compound 8) is a potent, selective and cell penetrant inhibitor of Protein Kinase N2 (PKN2, PRK2) with Ki/IC50 of 8/16 nM, shows 14-fold selectivity over PKN1.

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Biological Activity

PKN2-IN-1 (Compound 8) is a potent, selective and cell penetrant inhibitor of Protein Kinase N2 (PKN2, PRK2) with Ki/IC50 of 8/16 nM, shows 14-fold selectivity over PKN1.

Physicochemical Properties

M.Wt	241.29
Formula	C14H15N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-ethyl-2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one

References

1. Scott F, et al. Bioorg Med Chem Lett. 2022;60:128588.

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PKN2-IN-1

Biological Activity

Physicochemical Properties

References

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