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Cat. No. Product Name Information
PC-22530

RE104

5-HT2A agonist

Luvesilocin (RE104) is the prodrug of 4-OH-DiPT, a synthetic 5-hydroxytryptamine 2A receptor (5-HT2A receptor) agonist with Ki of 0.12 uM.
PC-22277

SB269970

5-HT7 antagonist

SB269970 (SB-269970) is a potent, selective 5-HT7 receptor antagonist with pKi of 8.9, >100-fold selective over other 5-HT receptors.
PC-21971

Bexicaserin

5-HT2C agonist

Bexicaserin (LP352) is a potent, highly selective, oral and centrally acting 5-HT2C receptor agonist with EC50 of 42 nM (Emax=112%), and Ki of 39 nM.
PC-21121

SB-271046

5-HT6 antagonist

SB-271046 is a potent, selective and orally active 5-HT6 receptor antagonist, potently displaces [(3)H]-LSD and [(125)I]-SB-258585 from human 5-HT6 receptors recombinantly expressed in HeLa cells with pKi 8.92 and 9.09 respectively.
PC-20963

Pimavanserin

5-HT2A inverse agonist

Pimavanserin (ACP-103) is a potent, selective, orally active 5-HT2A receptor inverse agonist, competitively antagonizes the binding of [(3)H]ketanserin to heterologously expressed human 5-HT(2A) receptors with pKi of 9.3 in membranes and 9.70 in whole cells.
PC-20844

EMD386088

5-HT6 agonist

EMD386088 is a potent, selective 5-HT6 receptor agonist with EC50 of 1.0 nM.
PC-49806

5-HT2A agonist (R)-70

5-HT2A agonist

5-HT2A agonist (R)-70 is a potent selective 5-HT2A receptor partial agonist with EC50 of 110 nM in calcium flux assays, and Ki value of 880 nM.
PC-49805

5-HT2A agonist (R)-69

5-HT2A agonist

5-HT2A agonist (R)-69 is a potent selective 5-HT2A receptor partial agonist with EC50 of 41 nM in calcium flux assays, and Ki value of 680 nM.
PC-49161

AS2030680

5-HT5A antagonist

AS2030680 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 0.58, 1.1 and 2.6 nM against human, rat, mouse 5-HT5A receptors, respectively.
PC-49160

ASP5736

5-HT5A antagonist

AS5736 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 3.6, 1.7 and 4.4 nM against human, rat, mouse 5-HT5A receptors, respectively.
PC-49159

AS2674723

5-HT5A antagonist

AS2674723 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 0.75, 0.67 and 1.9 nM against human, rat, mouse 5-HT5A receptors, respectively.
PC-49006

LY344864

5-HT1F agonist

LY344864 is a potent, selective agonist of 5-HT1F receptor with Ki value of 6 nM, with little to no affinity for other serotonergic and non-serotonergic neuronal binding sites.

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