| Cat. No. |
Product Name |
Information |
| PC-38716 |
SB-699551
5-HT5A antagonist
|
SB699551 is a potent, selective 5-HT5A receptor antagonist with pKi of 8.3, >100-fold selectivity over 5-HT1B/D, 5-HT2A, 5-HT2C, 5-HT1A and 5-HT7 receptors. |
| PC-73309 |
Vabicaserin
5-HT2C agonist
|
Vabicaserin (SCA-136) is a potent, selective 5-HT2C receptor full agonist with EC50 of 8 nM, Emax 100%. |
| PC-73308 |
NLX-101
5-HT1A agonist
|
NLX-101 (F15599) is a potent, highly selective post-synaptic 5-HT1A receptor agonist with Ki of 3.4 nM. |
| PC-73307 |
Felcisetrag
5-HT4 agonist
|
Felcisetrag (TAK-954, TD-8954) is a highly selective and potent 5-HT4 receptor agonist with pKi of 9.4 (human 5-HT4). |
| PC-73306 |
ASP2205
5-HT2C agonist
|
ASP2205 (ASP2205 fumarate) is a potent, selective 5-HT2C receptor agonist with EC50 of 0.85/2.5 nM for human/rat 5-HT2C in the intracellular Ca2+ mobilization assays, respectively. |
| PC-73305 |
PZ-1361
5-HT7 antagonist
|
PZ-1361 is a potent and selective 5-HT7 receptor antagonist with Ki of 33 nM, exhibit significant in vivo antidepressant and pro-cognitive properties in rodents. |
| PC-73304 |
AGH-192
5-HT7 agonist
|
AGH-192 is a potent, selective, orally bioavailable 5-HT7 receptor agonist with Ki of 4 nM. |
| PC-73303 |
AGH-107
5-HT7 agonist
|
AGH-107 is a potent, selective 5-HT7 receptor agonist with Ki of 6 nM and EC50 of 19 nM, 176-fold selectivity over 5-HT1AR. |
| PC-73302 |
AVN-492
5-HT6 antagonist
|
AVN-492 is a highly potent and selective 5-HT6 receptor antagonist with Ki of 91 pM, >1000-fold selectivity over 5-HT2BR (Ki=170 nM). |
| PC-73301 |
ST1936 oxalate
5-HT6 agonist
|
ST1936 oxalate is a potent, selective 5-HT6 receptor agonist with Ki of 13 nM, >10-fold selectivity over 5-HT7 and 5-HT2B receptors. |
| PC-73300 |
LP-211
5-HT7 agonist
|
LP-211 is a potent, selective, and BBB-penetrant 5-HT7 receptor agonist with Ki of 0.58 nM, high selectivity over 5-HT1A receptor (Ki, 188 nM) and D2 receptor (Ki, 142 nM). |
| PC-73299 |
Usmarapride
5-HT4 agonist
|
Usmarapride (SUVN-D4010) is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist with EC50of 44 nM. |
