| Cat. No. |
Product Name |
Information |
| PC-72159 |
TPN672
5-HT agonist
|
TPN672 (TPN 672) is a novel antipsychotic compound with high affinity for serotonin and dopamine receptors 5-HT1AR, (Ki=0.23 nM), 5-HT2AR (Ki=2.58 nM) as well as moderate affinity for D3R (Ki=11.55 nM) and D2R (Ki=17.91 nM). |
| PC-38060 |
SB 204741
5-HT2B antagonist
|
SB 204741 is a potent and selective 5-HT2B receptor antagonist (pA2=7.95). |
| PC-35384 |
EMD-281014 hydrochloride
5-HT2A antagonist
|
EMD-281014 hydrochloride ((Pruvanserin, LSN2411347, LY-2422347)) is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels. |
| PC-35383 |
EMD-281014
5-HT2A antagonist
|
EMD-281014 (Pruvanserin, LSN2411347, LY-2422347) is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels. |
| PC-43516 |
SB 242084 hydrochloride
5-HT2C antagonist
|
SB 242084 hydrochloride is a potent, selective, brain penetrant 5-HT2C receptor antagonist with pKi of 9.0, 100- and 158-fold selectivity over the closely related 5-HT2B and 5-HT2A subtypes. |
| PC-43515 |
SB 242084
5-HT2C antagonist
|
SB 242084 is a potent, selective, brain penetrant 5-HT2C receptor antagonist with pKi of 9.0, 100- and 158-fold selectivity over the closely related 5-HT2B and 5-HT2A subtypes. |
| PC-35022 |
SR57227 hydrochloride
5-HT3 agonist
|
SR-57227 is a high affinity, selective 5-HT3 receptor agonist, demonstrates anticonvulsant effects in vivo.. |
| PC-35021 |
SR-57227
5-HT3 agonist
|
SR-57227 is a high affinity, selective 5-HT3 receptor agonist, demonstrates anticonvulsant effects in vivo.. |
| PC-35019 |
Ro 60-0175 fumarate
5-HT2C agonist
|
Ro 60-0175 fumarate is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively. |
| PC-35018 |
Ro60-0175
5-HT2C agonist
|
Ro 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively. |
| PC-35004 |
PF-05212377
5-HT6 antagonist
|
PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with Ki of 0.32 nM (human 5HT6), shows potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease. |
| PC-63486 |
SB 258585 hydrochloride
5-HT6 antagonist
|
SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM, >160-fold selectivity over other 5-HT receptor subtypes. |
