| Cat. No. |
Product Name |
Information |
| PC-43382 |
WAY-100635 maleate
5-HT1A antagonist
|
WAY-100635 maleate is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor. |
| PC-62934 |
Perlapine
|
Perlapine (AW-14233, HF-2333, Hypnodine) is a potent antihistamine that has high affinity for dopamine D1, α1, α2 and 5-HT2A receptors with IC50 of 198, 19, 4945 and 70 nM, respectively. |
| PC-62760 |
SB 206553
5-HT2B/5-HT2C antagonist
|
SB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes. |
| PC-62097 |
Mosapride citrate
5HT4 agonist
|
Mosapride citrate (AS-4370 citrate) is a gastroprokinetic agent that acts as a selective 5HT4 agonist. |
| PC-62096 |
Naronapride
5-HT4 agonist
|
Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM. |
| PC-62094 |
Velusetrag
5-HT4 agonist
|
Velusetrag (TD-5108) is a potent, selective and oral 5-HT4 receptor agonist with pKi of 7.7, shows >500-fold selectivity over other 5-HT receptors. |
| PC-62093 |
YH12852
5-HT4 agonist
|
YH12852 is a potent, highly selective 5-HT4 receptor agonist with pKi of 10.3, exhibits more potent agonistic activity (pEC50=11.4) than both tegaserod and prucalopride. |
| PC-62010 |
VA-012
5-HT2C PAM
|
VA-012 is a potent, selective 5-HT2C receptor positive allosteric modulator (PAM) that exhibits dose-dependent potentiation of 5-HT efficacy with EC50 of 16 nM. |
| PC-61867 |
Eletriptan hydrobromide
5-HT1B/1D agonist
|
Eletriptan (UK 116044) hydrobromide is a potent, selective, and orally active 5-HT1B/1D receptor agonist with Ki of 0.92 nM and 3.14 nM respectively. |
| PC-61866 |
GR127935 hydrochloride
5-HT1B/1D antagonist
|
GR-127935 potent and selective 5-HT1B/1D receptor antagonist with pKi of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptor. |
| PC-61865 |
GR127935
5-HT1B/1D antagonist
|
GR127935 is a potent and selective 5-HT1B/1D receptor antagonist with pKi of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptor. |
| PC-61831 |
PF-04995274
|
PF-04995274 (TBPT) is a novel potent, sellective, partial agonist of 5-HT4 receptor under investigation for neurological disorders.. |
