PZ-1361 | 5-HT7 antagonist | Probechem Biochemicals

Chemical Structure : PZ-1361

PZ-1361 (PZ1361)

Catalog No.: PC-73305Not For Human Use, Lab Use Only.

PZ-1361 is a potent and selective 5-HT7 receptor antagonist with Ki of 33 nM, exhibit significant in vivo antidepressant and pro-cognitive properties in rodents.

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Biological Activity

PZ-1361 is a potent and selective 5-HT7 receptor antagonist with Ki of 33 nM, exhibit significant in vivo antidepressant and pro-cognitive properties in rodents.

Physicochemical Properties

M.Wt	501.038
Formula	C26H29ClN2O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-(3-([1,1'-biphenyl]-2-yloxy)-2-hydroxypropyl)piperidin-4-yl)-3-chlorobenzenesulfonamide

References

1. Vittorio Canale, et al. J Org Chem. 2020 Aug 21;85(16):10958-10965.

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PZ-1361 (PZ1361)

Biological Activity

Physicochemical Properties

References

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