| Cat. No. |
Product Name |
Information |
| PC-24517 |
N-0920
TMPRSS2 inhibitor
|
N-0920 (Cbz-QFR-kt) is highly potent, specific TMPRSS2 inhibitor with IC50 of 350 pM, displays high antiviral potency with IC50 of 0.3 nM and 0.09 nM for SARS-CoV-2 Variants EG.5.1 and JN.1 respectively. |
| PC-24314 |
JNJ-9676
SARS-CoV-2 M protein inhibitor
|
JNJ-9676 is a potent, specific small-molecule inhibitor of SARS-CoV-2 and SARS-CoV, binds to SARS-CoV-2 M protein, reduces SARS-CoV-2 (B1 variant) production of viral RNA with EC50/EC90 of 94/132 nM respectively. |
| PC-24313 |
CIM-834
SARS-CoV-2 M protein inhibitor
|
CIM-834 is a potent, first-in-class, orally efficacious small molecule coronavirus assembly inhibitor, blocks the assembly of SARS-CoV-2, targets the viral membrane (M) protein, inhibits replication of a panel of SARS-CoV-2 isolates with mean EC50 of 112 nM and 84 nM in VeroE6–GFP and A549ACE2+TMPRSS2 cells, respectively. |
| PC-23359 |
ATV014
SARS-CoV-2 RdRp inhibitor
|
ATV014 (SHEN26) is a potent, orally active anti-SARS-CoV-2 nucleoside compound with EC50 of 0.48 uM against SARS-CoV-2 replicon, inhibits SARS-CoV-2 RdRp. |
| PC-22947 |
AVI-4206
SARS-CoV-2 Mac1 inhibitor
|
AVI-4206 is a potent, specific small molecule inhibitor of SARS-CoV-2 ADP-ribosylhydrolase macrodomain (Mac1) with IC50 of 20 nM in HTRF assays. |
| PC-22802 |
EDP-235
3CLpro inhibitor
|
EDP-235 (Zevotrelvir, EDP235) is a potent, selective inhibitor of SARS-CoV-2 3CLpro with IC50 of 4.0 nM, Kiapp of 3.0 nM, reversibly binds and inhibits the 3CLpro. |
| PC-22258 |
PF-07817883
SARS-CoV-2 Mpro inhibitor
|
PF-07817883 (Ibuzatrelvir) is a second-generation, orally bioavailable, SARS-CoV-2 main protease (Mpro) with Ki value of 2.48 nM, EC50 of 180 nM for inhibition of SARS-CoV-2 induced cytopathic effect (CPE). |
| PC-22071 |
RAY1216
SARS-CoV-2 Mpro inhibitor
|
Leritrelvir (RAY1216) is a potent, selective peptidomimetic inhibitor of SARS-CoV-2 main protease (Mpro) with Ki of 8.4 nM. |
| PC-21780 |
CMX990
SARS-CoV-2 3CLpro inhibitor
|
CMX990 is a potent, selective and covalent SARS-CoV-2 3CLpro inhibitor with IC50 of 23.4 nM, exhibits good potency (EC50=37 nM) in HeLa-ACE2 SARS-CoV-2 assays. |
| PC-21710 |
AC1115
SARS-CoV-2 Mpro inhibitor
|
AC1115 is a potent, selective, next-generation antiviral targeting SARS-CoV-2 Mpro and host lysosomal cysteine protease cathepsin L (CTSL) with high antiviral activity, AC1115 is the active form of Olgotrelvir. |
| PC-21709 |
Olgotrelvir
SARS-CoV-2 Mpro inhibitor
|
Olgotrelvir (STI-1558) is a next-generation antiviral targeting SARS-CoV-2 Mpro and host lysosomal cysteine protease cathepsin L (CTSL) with high antiviral activity, Olgotrelvir is the prodrug of AC1115. |
| PC-21450 |
FB2001
SARS-CoV-2 Mpro inhibitor
|
Bofutrelvir (FB2001) is a potent, selective and covalent SARS-CoV-2 main protease (Mpro) inhibitor with IC50 value of 53 nM. |
