| Cat. No. |
Product Name |
Information |
| PC-22802 |
EDP-235
3CLpro inhibitor
|
EDP-235 (Zevotrelvir, EDP235) is a potent, selective inhibitor of SARS-CoV-2 3CLpro with IC50 of 4.0 nM, Kiapp of 3.0 nM, reversibly binds and inhibits the 3CLpro. |
| PC-22258 |
PF-07817883
SARS-CoV-2 Mpro inhibitor
|
PF-07817883 (Ibuzatrelvir) is a second-generation, orally bioavailable, SARS-CoV-2 main protease (Mpro) with Ki value of 2.48 nM, EC50 of 180 nM for inhibition of SARS-CoV-2 induced cytopathic effect (CPE). |
| PC-21710 |
AC1115
SARS-CoV-2 Mpro inhibitor
|
AC1115 is a potent, selective, next-generation antiviral targeting SARS-CoV-2 Mpro and host lysosomal cysteine protease cathepsin L (CTSL) with high antiviral activity, AC1115 is the active form of Olgotrelvir. |
| PC-21709 |
Olgotrelvir
SARS-CoV-2 Mpro inhibitor
|
Olgotrelvir (STI-1558) is a next-generation antiviral targeting SARS-CoV-2 Mpro and host lysosomal cysteine protease cathepsin L (CTSL) with high antiviral activity, Olgotrelvir is the prodrug of AC1115. |
| PC-21450 |
FB2001
SARS-CoV-2 Mpro inhibitor
|
Bofutrelvir (FB2001) is a potent, selective and covalent SARS-CoV-2 main protease (Mpro) inhibitor with IC50 value of 53 nM. |
| PC-21243 |
Simnotrelvir
SARS-CoV-2 3CLpro inhibitor
|
Simnotrelvir (SSD8432, SIM0417) is a potent, selective, covalent and orally bioavailable SARS-CoV-2 3C-like protease (3CLpro) inhibitor with IC50 of 9 nM in enzymatic inhibition assays. |
| PC-21077 |
GS-441524
Viral RdRp inhibitor
|
GS-441524 (GS441524) is the active metabolite of Remdesivir, inhibits viral RNA dependent RNA polymerase (RdRp) from the Flaviviridae family. |
| PC-21075 |
GS-5245
Antiviral
|
GS-5245 (Obeldesivir, ATV006) is an orall bioavailable, 5'-isobutyryl ester prodrug of GS-441524, exhibits strong SARS-CoV-2 antiviral efficacy both in vitro and in vivo. |
| PC-49865 |
TKB248
SARS-CoV-2 Mpro inhibitor
|
TKB248 (TKB-248) is a potent, specific SARS-CoV-2 Mpro inhibitor with IC50 of 74 nM, exhibits highly potent anti-SARS-CoV-2 activity with EC50 and EC95 values of 0.22 and 0.87 µM, respectively. |
| PC-49864 |
TKB245
SARS-CoV-2 Mpro inhibitor
|
TKB245 (TKB-245) is a potent, specific SARS-CoV-2 Mpro inhibitor with IC50 of 7 nM, exhibits highly potent anti-SARS-CoV-2 activity with EC50 and EC95 values of 0.03 and 0.53 µM, respectively. |
| PC-49668 |
WNN2048-F004
SARS-CoV-2 Mpro inhibitor
|
WNN2048-F004 (Compound 4a) is a potent, covalent, nonpeptidomimetic SARS-CoV-2 main protease (Mpro) inhibitor with biochemical IC50 of 103 nM, covalently binds to the substrate-binding pocket (Cys145) of SARS-CoV-2 Mpro. |
| PC-49579 |
Mpro inhibitor GD-9
SARS-CoV-2 Mpro inhibitor
|
Mpro inhibitor GD-9 is a potent, covalent SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.18 uM, exhibits antiviral potency against SARS-CoV-2 with EC50 of 2.64 uM. |
