| Cat. No. |
Product Name |
Information |
| PC-22009 |
ML2006a4
SARS-CoV-2 Mpro inhibitor
|
ML2006a4 is a highly potent, selective and orally bioavailable SARS-CoV-2 main protease (Mpro) inhibitor with IC50/Ki of 1.05/0.26 nM, shows antiviral EC50 value of 100-120 nM in Huh7.5.1-ACE2-TMPRSS2 cells. |
| PC-21878 |
GC-373
SARS-CoV-2 Mpro inhibitor
|
GC373 is a potent, covalent inhibitor of SARS CoV-2 main protease (MPro) with Kd of 0.15 uM, the reactive aldehyde form of GC376. |
| PC-21803 |
MK-7845
SARS-CoV-2 3CLPro inhibitor
|
MK-7845 is a potent, reversible covalent SARS-CoV-2 3CLPro inhibitor with IC50 of 8.7 nM, inhibits wild-type SARS-CoV-2 3CLPro in SARS-CoV-2 reporter replicon assay in A549 cells with IC50 of 15 nM. |
| PC-21780 |
CMX990
SARS-CoV-2 3CLpro inhibitor
|
CMX990 is a potent, selective and covalent SARS-CoV-2 3CLpro inhibitor with IC50 of 23.4 nM, exhibits good potency (EC50=37 nM) in HeLa-ACE2 SARS-CoV-2 assays. |
| PC-21710 |
AC1115
SARS-CoV-2 Mpro inhibitor
|
AC1115 is a potent, selective, next-generation antiviral targeting SARS-CoV-2 Mpro and host lysosomal cysteine protease cathepsin L (CTSL) with high antiviral activity, AC1115 is the active form of Olgotrelvir. |
| PC-21690 |
MDOLL-0229
SARS-CoV-2 Mac1 inhibitor
|
MDOLL-0229 is a selective small molecule inhibitor for SARS-CoV-2 Mac1 with IC50 of 2.1 uM, inhibits coronavirus replication. |
| PC-21479 |
JC19
SARS-CoV-2 nsp14 degrader
|
JC19 is a a cysteine-reactive small molecule degrader of SARS-CoV-2 nsp14 with DC50 of 8.7 uM in HEK293T cells. |
| PC-21451 |
GC-78-HCl
SARS-CoV-2 Mpro inhibitor
|
GC-78-HCl is a potent nonpeptide SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.19 uM, exhibits excellent antiviral activity (EC50=0.4 uM). |
| PC-21450 |
FB2001
SARS-CoV-2 Mpro inhibitor
|
Bofutrelvir (FB2001) is a potent, selective and covalent SARS-CoV-2 main protease (Mpro) inhibitor with IC50 value of 53 nM. |
| PC-21419 |
Compound 212-148
TMPRSS2 inhibitor
|
Compound 212-148 a bispecific, dual inhibitor of both TMPRSS2 and cysteine proteases cathepsin L/B (CTSL/CTSB) with IC50 of 1.38 uM and 2.13/64.07 nM, respectively, demonstrates antiviral activity against various SARS-CoV-2 variants. |
| PC-21335 |
MAT-POS-e194df51-1
SARS-CoV-2 Mpro inhibitor
|
MAT-POS-e194df51-1 is potent, selective and noncovalent SARS-CoV-2 main protease (SARS-CoV-2 Mpro) inhibitor with IC50 of 36.8 nM, shows antiviral activity with EC50 of 64 nM in A549-ACE2-TMPRSS2 cells. |
| PC-21248 |
Pomotrelvir
SARS-CoV-2 Mpro inhibitor
|
Pomotrelvir (PBI-0451) is a potent competitive inhibitor of SARS-CoV-2 Mpro (Ki=2.7 nM) with high selectivity against human proteases, inhibits wild-type SARS-CoV-2 Mpro with IC50 of 24 nM. |
