(S)-chlorcyclizine | SARS CoV fusion inhibitor

Chemical Structure : (S)-chlorcyclizine

(S)-chlorcyclizine ((S)-CCZ)

Catalog No.: PC-72893Not For Human Use, Lab Use Only.

(S)-chlorcyclizine ((S)-CCZ) is an approved antihistamine drug that is related to dichlorcyclizine (DCCZ), inhibits SARS-CoV and SARS-CoV-2 S-mediated infection in MA104 cells with EC50 of 6.91 and 4.09 uM.

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Biological Activity

(S)-chlorcyclizine ((S)-CCZ) is an approved antihistamine drug that is related to dichlorcyclizine (DCCZ), inhibits SARS-CoV and SARS-CoV-2 S-mediated infection in MA104 cells with EC50 of 6.91 and 4.09 uM.

Physicochemical Properties

M.Wt	300.83
Formula	C18H21ClN2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-1-((4-chlorophenyl)(phenyl)methyl)-4-methylpiperazine

References

1. Park SB, et al. mBio. 2022 Jan 11;13(1):e0323821.

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(S)-chlorcyclizine ((S)-CCZ)

Biological Activity

Physicochemical Properties

References

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