| Cat. No. |
Product Name |
Information |
| PC-24643 |
T1742
ATG5 inhibitor, Autophagy inhibitor
|
T1742 is a small molecule ATG5 inhibitor, blocks the ATG5-ATG16L1 and ATG5-TECAIR interactions in vitro (IC50=1-2 uM), effectively inhibits autophagy in living cells. |
| PC-20824 |
ATG12-ATG3 inhibitor 189
ATG12-ATG3 inhibitor
|
ATG12-ATG3 inhibitor 189 (Compound 189) is a selective inhibitor of autophagy targeting ATG12-ATG3 protein-protein interaction with IC50 of 9.3 uM. |
| PC-20716 |
DC-ATG4in
ATG4B inhibitor
|
DC-ATG4in is a small molecule autophagy related 4B (ATG4B) inhibitor, directly binds to ATG4B and inhibits its enzyme activity with IC50 of 3.08 uM, DC-ATG4in is an autophagy inhibitor. |
| PC-72137 |
Atg4B inhibitor 21f
ATG4B inhibitor
|
Atg4B inhibitor 21f is a potent competitive inhibitor for Atg4B with Ki of 3.1 uM. |
| PC-72136 |
UAMC-2526
ATG4B inhibitor
|
UAMC-2526 (UAMC2526) is a low micromolar ATG4B and autophagy inhibitor. |
| PC-35632 |
S130
ATG4B inhibitor
|
S130 (ATG4B inhibitor S130) is a potent, specific ATG4B inhibitor with IC50 of 3.24 uM, shows strong affinity (Kd=4 uM) and specifically suppresses the activity of ATG4B, but not other proteases. |
| PC-35540 |
LV-320
ATG4B inhibitor
|
LV-320 (LV320) is a novel potent, cell-active, allosteric inhibitor of the autophagy-related cysteine protease ATG4B with IC50 of 24.5 uM in ATG4B cleavage assays. |
| PC-60598 |
NSC 377071
ATG4B inhibitor
|
NSC 377071 (NSC-377071, NSC377071, Cambendazole) is a novel ATG4B antagonist that inhibits autophagy, with no effect on mTOR and PI3K activities. |
| PC-60597 |
NSC 185058
ATG4B inhibitor
|
NSC 185058 (NSC185058, NSC-185058, 2-Pyridinecarbothioamide) is a novel ATG4B antagonist that inhibits autophagy with IC50 of 50 uM, with no effect on mTOR and PI3K activities. |
| PC-42186 |
FMK-9a
ATG4B inhibitor
|
FMK-9a (FMK9a) is a potent, selective, covalent peptidomimetic inhibitor of ATG4B (Autophagin-1) with IC50 of 80 nM in TR-FRET assay. |
| PC-23000 |
ATG12-ATG3 inhibitor Compound 4
ATG12-ATG3 inhibitor
|
ATG12-ATG3 inhibitor Compound 4 is a small molecule inhibitor of ATG12-ATG3 protein-protein interaction with IC50 of 9 uM. |
