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Cat. No. Product Name CAS No. Information
PC-72388

PF-05221304

1370448-25-1 PF-05221304 (PF 05221304) is a novel potent, selective, liver-targeted dual acetyl-CoA carboxylase (ACC1/2) inhibitor with IC50 of 13/9 nM (hACC1/2).
PC-61377

Firsocostat

1434635-54-7 Firsocostat (ND-630, NDI-010976, GS-0976) is a highly potent, selective inhibitor of acetyl-CoA carboxylase (ACC) with IC50 of 2.1 and 6.1 nM for isozymes ACC1 and ACC2, respectively.
PC-42306

TOFA

54857-86-2 TOFA (RMI14514, MDL14514) is an indirect, allosteric inhibitor of Acetyl-CoA carboxylase-α (ACCA) and fatty acid synthesis.
PC-73298

ACC2 inhibitor 2e

2237229-78-4 ACC2 inhibitor 2e is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 1.9 nM and 1950 nM for ACC2 and ACC1, respectively.
PC-73297

A-908292

903886-95-3 A-908292 is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 38 nM (hACC2), no activity against ACC1 (IC50>30 uM).
PC-72818

IMA-1

2315406-63-2 IMA-1 (ALOX12-ACC1 inhibitor IMA-1) is a small molecule that interrupt the arachidonate 12-lipoxygenase (ALOX12)-acetyl-CoA carboxylase 1 (ACC1) interaction.
PC-72105

ACC1 inhibitor Compound 1

2020325-26-0 ACC1 inhibitor Compound 1 is a potent, highly selective, oral ACC1 inhibitor with IC50 of 0.58 nM (hACC1), no effect on hACC2 (IC50>10 uM).

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