Chemical Structure : A-908292
CAS No.: 903886-95-3
Catalog No.: PC-73297Not For Human Use, Lab Use Only.
A-908292 is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 38 nM (hACC2), no activity against ACC1 (IC50>30 uM).
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A-908292 is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 38 nM (hACC2), no activity against ACC1 (IC50>30 uM).
M.Wt | 360.428 | |
Formula | C18H20N2O4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Carbamic acid, N-[(1S)-1-methyl-3-[2-[4-(1-methylethoxy)phenoxy]-5-thiazolyl]-2-propyn-1-yl]-, methyl ester |
1. Nishiura Y, et al. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2498-2503.
2. Takagi H, et al. J Pharmacol Exp Ther. 2020 Mar;372(3):256-263.
3. Waring JF, et al. J Pharmacol Exp Ther. 2008 Feb;324(2):507-16.
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