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Cat. No. Product Name Information
PC-49742

NS3694

Caspase inhibitor

NS3694 (NS 3694) is a specific cell-permeable diarylurea compound that inhibits apoptosome formation and caspase activation, blocks cytochrome c-induced caspase activation in HeLa cell cytosolic extracts with IC50 of 50 uM.
PC-73051

Procaspase-6 inhibitor 13

Procaspase-6 inhibitor

Procaspase-6 inhibitor 13 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.38 uM.
PC-73050

Procaspase-6 inhibitor 12

Procaspase-6 inhibitor

Procaspase-6 inhibitor 12 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.47 uM.
PC-73049

PG3d

Caspase-6 inhibitor

PG3d (Caspase-6 inhibitor PG3d) is a cell-active, allosteric and irreversible, non-competitive Caspase-6 inhibitor.
PC-72960

NH-23-C2

Caspase-2 inhibitor

NH-23-C2 (Caspase-2 inhibitor NH-23-C2) is a potent, selective and cell-permeable endogenous caspase-2 inhibitor, does not block caspase-3 or caspase-8.
PC-63279

ML132

Caspase-1 inhibitor

ML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases..
PC-43410

BOC-D-FMK

Caspase inhibitor

BOC-D-FMK is a cell-permeable, irreversible, broad spectrum caspase inhibitor, inhibits apoptosis stimulated by TNF-α with IC50 of 39 uM.
PC-43391

VX-765

Caspase-1 inhibitor

VX-765 (Belnacasan) is an orally absorbed prodrug of VRT-043198, which is a potent and selective inhibitor of interleukin-converting enzyme/caspase-1 with Ki of 0.8 nM.
PC-43046

Z-DEVD-FMK

Caspase-3 inhibitor

Z-DEVD-FMK is a specific caspase-3 inhibitor with IC50 of 18 uM, inhibits apoptosis.
PC-42968

Q-VD-Oph

pan-Caspase inhibitor

Q-VD-Oph is a potent pan-caspase inhibitor, inhibits human recombinant caspase-7 with IC50 of 48 nM in cell-free assay, also inhibits caspase -1, 3, 8, 9, 10, and 12 with IC50 of 25-400 nM.
PC-62433

Emricasan

Caspase inhibitor

Emricasan (IDN-6556, PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.
PC-62211

WF-210

Procaspases-3 activator

WF-210 is a PAC-1 derivative and potent activator of procaspases-3 with EC50 of 0.95 uM, displays more cytotoxic than PAC‐1 to human cancer cells, but less cytotoxic to normal cells.

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