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Chemical Structure : Z-DEVD-FMK
CAS No.: 210344-95-9
Catalog No.: PC-43046Not For Human Use, Lab Use Only.
Z-DEVD-FMK is a specific caspase-3 inhibitor with IC50 of 18 uM, inhibits apoptosis.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $88 | In stock | |
| 5 mg | $198 | In stock | |
| 10 mg | $328 | In stock | |
| 25 mg | Get quote |
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Z-DEVD-FMK is a specific caspase-3 inhibitor with IC50 of 18 uM, inhibits apoptosis.
Z-DEVD-FMK affects the survival and function of platelets in platelet concentrate during storage, blocks the geranylgeraniol-induced DNA fragmentation in human leukemia cells.
Z-DEVD-FMK abolishes the apoptosis, CPP32/Mch3alpha processing and the increase in CPP32-like protease activity induced by TGF-beta1 in rat hepatocytes.
| M.Wt | 668.6646 | |
| Formula | C30H41FN4O12 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 33.33 mg/mL |
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| Chemical Name/SMILES |
L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-α-aspartyl-L-α-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, 1,2-dimethyl ester |
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1. Inayat-Hussain SH, et al. Hepatology. 1997 Jun;25(6):1516-26.
2. Lee YS, et al. Mol Cells. 1998 Jun 30;8(3):272-9.
3. Kanthasamy AG, et al. Free Radic Biol Med. 2006 Nov 15;41(10):1578-89.
4. Springer JE, et al. Nat Med. 1999 Aug;5(8):943-6.
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