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Cat. No. Product Name Information
PC-73375

M3541

M3541 (M 3541) is a novel potent, selective and ATP-competitive ATM kinase inhibitor with IC50 of 0.25 nM (ATP, 10 uM).
PC-72900

M4076

Lartesertib (M4076) is a higly potent, selective, ATP-competitive inhibitor of ATM kinase with IC50 of 0.2 nM.
PC-72315

RP-3500

RP-3500 (RP3500, Camonsertib) is a novel potent, selective, orally bioavailable ATR inhibitor with IC50 of 1.0 and 0.33 nM in biochemical and cell-based assays, respectively.
PC-72164

M6620

M6620 (Berzosertib, VX-970, VE-822) is a highly potent, selective ATR inhibitor with Ki of 0.17 nM, pH2AX IC50 of 19 nM.
PC-72163

M4344

M4344 (VX-803, Gartisertib) is a highly potent, selective ATR inhibitor with Ki<0.15 nM.
PC-42876

KU-60019

KU-60019 is an improved analogue of KU-55933, and is a potent, specific inhibitor of ATM kinase with IC50 of 6.3 nM, 270- and 1,600-fold selectivity over DNA-PKcs and ATR.
PC-42831

KU-55933

KU-55933 (KU55933) is a potent, specific, ATP-competitive inhibitor of ATM with Ki/IC50 of 2.2/13 nM, >100-fold selectivity against other members of the PIKK family kinases.

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