| Cat. No. |
Product Name |
Information |
| PC-42831 |
KU-55933
ATM inhibitor
|
KU-55933 (KU55933) is a potent, specific, ATP-competitive inhibitor of ATM with Ki/IC50 of 2.2/13 nM, >100-fold selectivity against other members of the PIKK family kinases. |
| PC-62548 |
GSK635416A
ATM inhibitor
|
GSK 635416A is a novel ATM inhibitor with highly selective radiosensitizing activity, inhibits radiation induced phosphorylation of ATM. |
| PC-61826 |
AZD1390
ATM inhibitor
|
AZD1390 (AZD-1390) is a novel potent, selective, orally available and CNS penetrant ATM inhibitor with IC50 of 0.78 nM, displays >1,000-fold selectivity over closely related (PIKKs) and distant kinases. |
| PC-70146 |
BAY-1895344 hydrochloride
ATR inhibitor
|
BAY-1895344 (Elimusertib) hydrochloride is a potent, selective, orally active ATR inhibitor with low-nanomolar potency (IC50=7 nM). |
| PC-70111 |
ATM inhibitor AZ31
ATM inhibitor
|
AZ31 is a potent, highly selective and orally active ATM inhibitor with enzyme IC50 of <1.2 nM, cell IC50 of 46 nM. |
| PC-70110 |
CBP-93872
G2 checkpoint inhibitor
|
CBP-93872 is a potent G2 checkpoint inhibitor that specifically abrogates the DNA double-stranded break (DSB)-induced G2 checkpoint, inhibits NBS1-mediated ATR activation. |
| PC-60277 |
BAY 1895344
ATR inhibitor
|
BAY 1895344 (BAY-1895344, Elimusertib) is a novel potent, highly selective ATR kinase inhibitor with IC50 of 7.0 nM. |
| PC-44042 |
VE-821
ATR inhibitor
|
VE-821 (VE821) is a potent, selective and ATP-competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM, respectively. |
| PC-42030 |
AZD0156
ATM inhibitor
|
AZD0156 (AZD-0156) is a potent, highly selective and orally bioavailable ATM kinase inhibitor with IC50 of 0.58 nM. |
| PC-45607 |
AZD6738
ATR inhibitor
|
AZD6738 (Ceralasertib) is a potent and selective inhibitor of ATR with IC50 of 1 nM. |
| PC-42778 |
CP-466722
ATM inhibitor
|
CP-466722 is a poten and selective ATM inhibitor (IC50=0.41 uM) without effect on ATR kinase, does not inhibit PI3K, PI3K-like protein kinases or Abl kinase. |
| PC-42333 |
GJ103 sodium salt
Read-through compound
|
GJ103 sodium salt is a novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene. |
