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Chemical Structure : GSK 635416A
Catalog No.: PC-62548Not For Human Use, Lab Use Only.
GSK 635416A is a novel ATM inhibitor with highly selective radiosensitizing activity, inhibits radiation induced phosphorylation of ATM.
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GSK 635416A is a novel ATM inhibitor with highly selective radiosensitizing activity, inhibits radiation induced phosphorylation of ATM; exhibits virtually no cytotoxicity in the absence of radiation and in normal fibroblast cells, enhances IR effect in radiosensitizing HNSCC cell lines but not in normal fibroblast BJ-ET cells in combined with olaparib.
| M.Wt | 453.532 | |
| Formula | C24H24FN3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dohmen AJC, et al. Oncotarget. 2017 May 19;8(43):73925-73937.
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