| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-38421 |
Selnoflast
|
2260969-36-4 |
Selnoflast is a potent, selective NLRP3 inhibitor. |
| PC-35137 |
CY-09
|
1073612-91-5 |
CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor, binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity. |
| PC-43228 |
MCC950
|
210826-40-7 |
MCC950 (CP-456773) is a potent, selective, small-molecule inhibitor of NLRP3 inflammasome with IC50 of 7.5 and 8.1 nM in BMDM and HMDM, respectively, specifically inhibits activation of NLRP3, does not inhibit NLRC4, AIM2, TLR signalling or priming of NLRP3. |
| PC-42228 |
NOD-IN-1
|
132819-92-2 |
NOD-IN-1 is a potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively. |
| PC-45499 |
Nodinitib-1
|
799264-47-4 |
Nodinitib-1 (ML130) is a potent and selective NOD1 inhibitor with IC50 of 0.56 uM. |
| PC-49812 |
ML146
|
1164540-96-8 |
ML146 (ML-146, Pubmed CID-1088438) is a selective small molecule NOD1 inhibitor with IC50 of 1.5 uM in NOD1 agonist-stimulated NF-κB reporter assay in HEK293T cells. |
| PC-49811 |
GSK223
|
899758-61-3 |
GSK223 (GSK-223) is a specific small molecule inhibitor of the NOD1 signaling pathway, shows NOD1 inhibitory activity with IC50 of 1 uM in 293/hNOD1 cell assays, does not inhibit RIP2 kinase. |
