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Cat. No. Product Name CAS No. Information
PC-38421

Selnoflast

2260969-36-4 Selnoflast is a potent, selective NLRP3 inhibitor.
PC-35137

CY-09

1073612-91-5 CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor, binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity.
PC-43228

MCC950

210826-40-7 MCC950 (CP-456773) is a potent, selective, small-molecule inhibitor of NLRP3 inflammasome with IC50 of 7.5 and 8.1 nM in BMDM and HMDM, respectively, specifically inhibits activation of NLRP3, does not inhibit NLRC4, AIM2, TLR signalling or priming of NLRP3.
PC-42228

NOD-IN-1

132819-92-2 NOD-IN-1 is a potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively.
PC-45499

Nodinitib-1

799264-47-4 Nodinitib-1 (ML130) is a potent and selective NOD1 inhibitor with IC50 of 0.56 uM.
PC-49812

ML146

1164540-96-8 ML146 (ML-146, Pubmed CID-1088438) is a selective small molecule NOD1 inhibitor with IC50 of 1.5 uM in NOD1 agonist-stimulated NF-κB reporter assay in HEK293T cells.
PC-49811

GSK223

899758-61-3 GSK223 (GSK-223) is a specific small molecule inhibitor of the NOD1 signaling pathway, shows NOD1 inhibitory activity with IC50 of 1 uM in 293/hNOD1 cell assays, does not inhibit RIP2 kinase.

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