NOD-like Receptor (NLR) (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-22372	NT-0249 NLRP3 inhibitor	NT-0249 is a potent, specific NLRP3 inhibitor, potently inhibits palmitate-driven IL-1β release from human PBMCs with IC50 of 11 nM.
PC-22042	NLRP3 inhibitor NIC-11 NLRP3 inhibitor	NIC-11 is a highly potent broad-spectrum NLRP3 inhibitor, inhibits NLRP3 inflammasome activation (IL-1β release) in mouse macrophages with IC50 of 69 nM.
PC-22041	NLRP3 inhibitor NIC-12 NLRP3 inhibitor	NIC-12 is a highly potent broad-spectrum NLRP3 inhibitor, inhibits NLRP3 inflammasome activation (IL-1β release) in mouse macrophages with IC50 of 11 nM.
PC-21813	NDT-19795 NLRP3 inhibitor	NDT-19795 is the carboxylic acid metabolite of selective NLRP3 inhibitor NT-0796, suppresses release of IL-1β in LPS-activated human PBMCs with IC50 of 47 nM.
PC-21282	DFV890 NLRP3 inhibitor	DFV890 (IFM-2427) is apotent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation,prevents NLRP3 inflammasome assembly in response to sterile danger signals.
PC-21079	JT002 NLRP3 inhibitor	JT002 is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of 6 nM (IL-1β production from hPBMCs), inhibits NLRP3 mediated cytokine production and pyroptosis.
PC-20912	JT001 NLRP3 inhibitor	JT001 (JT-001) is a potent, highly specific NLRP3 inhibitor, inhibits NLRP3 inflammasome assembly.

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