| Cat. No. |
Product Name |
Information |
| PC-23200 |
YM-I-26
NLRP3 inhibitor
|
YM-I-26 is a highly selective NLRP3 inflammasome inhibitor, binds to recombinant NLRP3 with Kd of 560.2 nM. |
| PC-22764 |
INF200
NLRP3 inhibitor
|
INF200 is a novel sulfonylurea-based NLRP3 inhibitor, specifically inhibits NLRP3-driven pyroptosis with IC50 of 1.55 uM, efficiently reduces cardiac and metabolic complications in in vivo model of diet-induced metaflammation. |
| PC-22763 |
INF195
NLRP3 inhibitor
|
INF195 is a small molecule NLRP3 inhibitor, specifically inhibits NLRP3-driven pyroptosis and IL-1 β release in human macrophages. |
| PC-22372 |
NT-0249
NLRP3 inhibitor
|
NT-0249 is a potent, specific NLRP3 inhibitor, potently inhibits palmitate-driven IL-1β release from human PBMCs with IC50 of 11 nM. |
| PC-22042 |
NLRP3 inhibitor NIC-11
NLRP3 inhibitor
|
NIC-11 is a highly potent broad-spectrum NLRP3 inhibitor, inhibits NLRP3 inflammasome activation (IL-1β release) in mouse macrophages with IC50 of 69 nM. |
| PC-22041 |
NLRP3 inhibitor NIC-12
NLRP3 inhibitor
|
NIC-12 is a highly potent broad-spectrum NLRP3 inhibitor, inhibits NLRP3 inflammasome activation (IL-1β release) in mouse macrophages with IC50 of 11 nM. |
| PC-21813 |
NDT-19795
NLRP3 inhibitor
|
NDT-19795 is the carboxylic acid metabolite of selective NLRP3 inhibitor NT-0796, suppresses release of IL-1β in LPS-activated human PBMCs with IC50 of 47 nM. |
| PC-21079 |
JT002
NLRP3 inhibitor
|
JT002 is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of 6 nM (IL-1β production from hPBMCs), inhibits NLRP3 mediated cytokine production and pyroptosis. |
| PC-20912 |
JT001
NLRP3 inhibitor
|
JT001 (JT-001) is a potent, highly specific NLRP3 inhibitor, inhibits NLRP3 inflammasome assembly. |
