| Cat. No. |
Product Name |
Information |
| PC-49713 |
SW120619
WNK3 inhibitor
|
SW120619 is a specific small molecule inhibitor of WNK3 kinase with IC50 of 0.7 uM, weakly inhibits WNK1 and WNK2 with IC50 of 2.3 and 16.8 uM, respectively. |
| PC-49712 |
SW118150
WNK3 inhibitor
|
SW118150 is a selective small molecule inhibitor of WNK3 kinase with IC50 of 3.0 uM, 5-fold selectivity over WNK1. |
| PC-61065 |
WNK inhibitor 7
WNK1 inhibitor
|
WNK inhibitor 7 (WNK-IN-7) is a potent, selectiive inhibitor of WNK1 kinase with IC50 of 95 nM, shows IC50 of 1.39 uM in the cellular OSR1 phosphorylation assay with reasonable aqueous solubility. |
| PC-61064 |
WNK inhibitor 11
WNK inhibitor
|
WNK inhibitor 11 is a potent, selectiive and orally active inhibitor of WNK1 kinase with IC50 of 6 nM, 1,000-fold selectivity over WNK4 and 57-fold selectivity over WNK2. |
| PC-42214 |
WNK463
WNK inhibitor
|
WNK463 is the first, potent, selective, and orally bioavailable pan With-No-Lysine (WNK) Kinase catalytic activity inhibitor with IC50 of 5/1/6/9 nM for WNK1/2/3/4, respectively. |
