WNK inhibitor 7 |CAS:2125724-72-1 Probechem Biochemicals

Chemical Structure : WNK inhibitor 7

WNK inhibitor 7 (WNK-IN-7)

Catalog No.: PC-61065Not For Human Use, Lab Use Only.

WNK inhibitor 7 (WNK-IN-7) is a potent, selectiive inhibitor of WNK1 kinase with IC50 of 95 nM, shows IC50 of 1.39 uM in the cellular OSR1 phosphorylation assay with reasonable aqueous solubility.

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Biological Activity

WNK inhibitor 7 (WNK-IN-7) is a potent, selectiive inhibitor of WNK1 kinase with IC50 of 95 nM, shows IC50 of 1.39 uM in the cellular OSR1 phosphorylation assay with reasonable aqueous solubility.

Physicochemical Properties

M.Wt	399.538
Formula	C26H29N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((1-(2-(3-methoxyphenyl)-5-methylpyridin-4-yl)-1H-indol-3-yl)methyl)-2-methylpropan-1-amine

References

1. Yamada K, et al. ACS Chem Biol. 2016 Dec 16;11(12):3338-3346.

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WNK inhibitor 7 (WNK-IN-7)

Biological Activity

Physicochemical Properties

References

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