| Cat. No. |
Product Name |
Information |
| PC-20515 |
Sparsentan
Dual AT-II and ETA antagonist
|
Sparsentan (RE-021, DARA-a) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Ki values of 0.8 and 9.3 nM, respectively. |
| PC-49657 |
Forasartan
AT1 receptor inhibitor
|
Forasartan (SC-52458) is a potent, specific, competitive and reversible angiotensin II receptor (AT1 receptor) antagonist with binding Ki value of 2.9 nM. |
| PC-73402 |
Azilsartan mopivabil
AT2R antagonist
|
Azilsartan mopivabil is a potent, selective angiotensin II receptor (AT2R) antagonist, with potential for hypertension, chronic heart failure and diabetic nephropathy. |
| PC-73401 |
Azilsartan mepixetil
AT2R antagonist
|
Azilsartan mepixetil is a potent, selective angiotensin II receptor antagonist, with potential for hypertension, chronic heart failure and diabetic nephropathy. |
| PC-72732 |
DCP1-3
AT1R allosteric modulator
|
DCP1-3 is a novel allosteric ligand of the angiotensin receptor AT1R, displays NAM potency on AngIV with IC50 of 0.29 uM. |
| PC-43383 |
EMA401
AT2R inhibitor
|
EMA401 (Olodanrigan) is a potent, highly selective angiotensin II type 2 receptor (AT2R) antagonist, inhibits capsaicin responses in cultured neurons of human and rat DRG with IC50 of 10 nM. |
| PC-62642 |
EMA300
AT2 receptor antagonist
|
EMA300 (PD121981) is a potent, selective small molecule antagonist of angiotensin II type 2 receptor (AT2R) with >1,000-fold selectivity over AT1 receptor. |
| PC-44124 |
Azilsartan
AT1 inhibitor
|
Azilsartan (TAK-536) is a specific and potent angiotensin II type 1 receptor (AT1) antagonist with IC50 of 2.6 nM, used in the treatment of adults with essential hypertension. |
| PC-45316 |
Losartan
AT1 inhibitor, PAX8 inhibitor
|
Losartan (DuP-753) is a selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension), also inhibits PAX8 expression and function. |
| PC-23855 |
Irbesartan
AT1 receptor antagonist
|
Irbesartan (SR 47436) is a potent, selective nonpeptide AT1 angiotensin II receptor (AT1 receptor) antagonist, inhibits [125I]AII binding to AT1 subtype receptors in rat liver membrane with IC50 of 1.7 nM, with no effect on AT2 subtypes. |
| PC-23653 |
TRV120027 TFA
AT1R ligand
|
TRV027 TFA (TRV120027 TFA) is a potent, selective β-arrestin biased ligand of angiotensin II type 1 receptor (AT1R), competitively antagonizes angiotensin II-stimulated G protein signaling. |
| PC-23652 |
TRV027
AT1R ligand
|
TRV027 (TRV120027) is a potent, selective β-arrestin biased ligand of angiotensin II type 1 receptor (AT1R), competitively antagonizes angiotensin II-stimulated G protein signaling. |
