| Cat. No. |
Product Name |
Information |
| PC-45317 |
Losartan potassium
AT1 inhibitor, PAX8 inhibitor
|
Losartan potassium (DuP-753) is a selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension), also inhibits PAX8 expression and function. |
| PC-45316 |
Losartan
AT1 inhibitor, PAX8 inhibitor
|
Losartan (DuP-753) is a selective, competitive angiotensin II receptor type 1 (AT1) antagonist (IC50=20 nM) for treatment of high blood pressure (hypertension), also inhibits PAX8 expression and function. |
| PC-42495 |
PD 123319 ditrifluoroacetate
AT2 receptor antagonist
|
PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin II type 2 receptor (AT2 receptor) antagonist with IC50 of 34 nM. |
| PC-42494 |
PD 123319
AT2 receptor antagonist
|
PD 123319 (PD123,319) potent, selective, non-peptide angiotensin II type 2 receptor (AT2 receptor) antagonist with IC50 of 34 nM. |
| PC-23855 |
Irbesartan
AT1 receptor antagonist
|
Irbesartan (SR 47436) is a potent, selective nonpeptide AT1 angiotensin II receptor (AT1 receptor) antagonist, inhibits [125I]AII binding to AT1 subtype receptors in rat liver membrane with IC50 of 1.7 nM, with no effect on AT2 subtypes. |
| PC-23653 |
TRV120027 TFA
AT1R ligand
|
TRV027 TFA (TRV120027 TFA) is a potent, selective β-arrestin biased ligand of angiotensin II type 1 receptor (AT1R), competitively antagonizes angiotensin II-stimulated G protein signaling. |
| PC-23652 |
TRV027
AT1R ligand
|
TRV027 (TRV120027) is a potent, selective β-arrestin biased ligand of angiotensin II type 1 receptor (AT1R), competitively antagonizes angiotensin II-stimulated G protein signaling. |
| PC-22028 |
BIO101
MasR agonist
|
BIO101 (20-hydroxyecdysone, Crustecdysone) is a small molecule agonist of Mas receptor (MasR), has anti-inflammatory, anti-fibrotic and cardioprotective properties, shows potential treatment for respiratory failure in COVID-19. |
| PC-21225 |
AVE-0991
Angiotensin-(1-7) agonist
|
AVE 0991 is a potent, selective nonpeptide and orally active angiotensin-(1-7) receptor Mas agonist, displaces the binding of 125I-Ang-(1-7) in Mas-transfected monkey kidney cells (COS) cells with IC50 of 47.5 nM. |
| PC-21224 |
A779
Angiotensin-(1-7) inhibitor
|
A779 is a potent, selective antagonist of angiotensin-(1-7) receptor Mas, blocks the antidiuretic effect of Ang-(1-7) in vivo. |
| PC-70201 |
Candesartan
|
An angiotensin II receptor antagonist used mainly for the treatment of hypertension.. |
| PC-45274 |
Azilsartan medoxomil monopotassium
|
An orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. . |
