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Chemical Structure : BIBS-39
CAS No.: 133085-33-3
Catalog No.: PC-45692Not For Human Use, Lab Use Only.
BIBS-39 is a selective nonpeptide angiotensin II receptor antagonist with Ki of 29 nM and 480 nM for AT1 and AT2 respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $288 | In stock | |
| 25 mg | $560 | In stock | |
| 50 mg | $728 | In stock |
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BIBS-39 is a selective nonpeptide angiotensin II receptor antagonist with Ki of 29 nM and 480 nM for AT1 and AT2 respectively; shows no high affinity for other receptors, shifts the AII concentration-contractile response curves in isolated rabbit aorta with pA2 of 8.14 and a slope of 1.06; shows effective antihypertensives in the model of the renal hypertensive rat.
| M.Wt | 524.6533 | |
| Formula | C32H36N4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 32 mg/mL |
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| Chemical Name/SMILES |
[1,1'-Biphenyl]-2-carboxylic acid, 4'-[[2-butyl-6-[[(cyclohexylamino)carbonyl]amino]-1H-benzimidazol-1-yl]methyl]- |
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1. Zhang J, et al. Eur J Pharmacol. 1992 Jul 21;218(1):35-41.
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