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Cat. No. Product Name Information
PC-21118

HDAC3 PROTAC P7

HDAC3 PROTAC P7 is a potent and selective HDAC3-directed PROTAC with IC50 of 40 nM (HDAC3 deacetylase activity), effectively induces HDAC3 degradation with DC50 of 0.6 nM in THP-1 cells (Emax=90%).
PC-20920

SJ3149

SJ3149 (SJ-3149) is uniquely potent and selective CK1α degrader with DC50 of 3.7 nM and Dmax 95% in MOLM-13 cells, potently inhibits the viability of MOLM-13 cells with IC50 of 13 nM.
PC-20684

BSJ-04-146

BSJ-04-146 is a potent, selective FAK PROTAC (IC50=26 nM), induces potent and durable FAK degradation in pancreatic and breast cancer cell lines at 10 nM.
PC-20665

ARV-766

ARV-776 (Luxdegalutamide, ARV776) is potent, orally bioavailable PROTAC androgen receptor (AR) degrader that degrades not only wild-type AR but also clinically relevant AR LBD mutants, including the most prevalent AR L702H, H875Y, and T878A mutations.
PC-20560

NX-2127

NX-2127 (NX2127) is a hetero-bifunctional, orally active PROTAC that induces the degradation of BTK and IKZF3 ubiquitination and proteasomal degradation in cells through recruitment of cereblon (CRBN).
PC-20356

UNC8153

UNC8153 (UNC 8153) is a selective NSD2-targeted degrader with binding Kd of 24 nM for NSD2, potently and selectively reduces cellular levels of both NSD2 protein (DC50=350 nM) and H3K36me2 chromatin mark.
PC-20168

ZZ151

ZZ151 (ZZ-151) is a highly potent and selective SOS1 degrader PROTAC with DC50 of 15.7 nM (Dmax=100%).

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