| Cat. No. |
Product Name |
Information |
| PC-60121 |
SNIPER(ABL)-062
BCR-ABL degrader
|
SNIPER(ABL)-062 is a novel, potent SNIPER molecule that tethers BCR-ABL inhibitor to a ligand of IAP, causes potent BCR-ABL degradation. |
| PC-60103 |
BETd-260 trifluoroacetate
BET PROTAC
|
BETd-260 trifluoroacetate (ZBC260, BETd 260 TFA) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL. |
| PC-60102 |
BETd-260
BET PROTAC
|
BETd-260 (ZBC260, BETd260) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL. |
| PC-60100 |
CDK9 PROTAC 1
CDK9 PROTAC
|
CDK9 PROTAC 1 is a heterobifunctional small molecule PROTAC capable of cereblon mediated proteasomal degradation of CDK9. |
| PC-60099 |
MZ1
BRD4 PROTAC
|
MZ1 is a PROTAC that tethers JQ1 to a ligand for the E3 ubiquitin ligase VHL, triggers and induces degradation of the BET bromodomain BRD4. |
| PC-60096 |
Sirt2 PROTAC 1
Sirt2 PROTAC
|
Sirt2 PROTAC 1 is a SirReal-based PROTAC that induces isotype-selective Sirt2 degradation (IC50=0.25 uM). |
| PC-42297 |
ARV-771
BET PROTAC
|
ARV-771 (ARV771) is a potent BET degrader (PROTAC), potently degrades BRD2/3/4 in 22Rv1 cells with DC50< 5 nM. |
| PC-45097 |
ARV-825
BRD4 PROTAC
|
ARV-825 is a hetero-bifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon, leading to fast, efficient, and prolonged degradation of BRD4 via the proteasome. |
| PC-25575 |
BRD9 degrader ZZ7
BRD9 degrader
|
BRD9 degrader ZZ7 is a specific, reversible covalent molecular glue degrader that selectively degrades BRD9, covalently engages DCAF16 at Cys178. |
| PC-25541 |
CDK9 degrader PO-8
CDK9 PROTAC
|
CDK9 degrader PO-8 is a potent, selective iCDK9-based PROTAC degrader of CDK9 with DC50 of 0.26 uM in RAW 264.7 cells. |
| PC-25535 |
dHTC3
BRD4 BD1 degrader
|
dHTC3 is a small molecule, FBXO3-dependent and BD1-specific BRD4 degrader, FBXO3 mediates BRD4 degradation by dHTC3. |
| PC-25534 |
(S)-dHTC1
ENL degrader
|
(S)-dHTC1 is a potent, selective, and stereochemistry-dependent degrader of Eleven-Nineteen-Leukemia protein (ENL) with binding Kd of 49 nM for ENL. |
