| Cat. No. |
Product Name |
Information |
| PC-38690 |
Zavegepant
CGRP antagonist
|
Zavegepant (Vazegepant, BHV-3500, BMS-742413) is a high affinity, selective antagonist of calcitonin gene-related peptide (CGRP) receptor (hCGRP, Ki=0.023 nM), has demonstrated efficacy in the acute treatment of migraine. |
| PC-72952 |
BMS-846372
CGRP antagonist
|
BMS-846372 (BMS846372) is a potent, selective, orally active CGRP receptor antagonist with Ki of 0.07 nM (hCGRP). |
| PC-72787 |
FE 205030
CGRP antagonist
|
FE 205030 (FE205030) is a potent, selective peptidic CGRP antagonist with IC50 of 0.2 nM. |
| PC-35253 |
Ubrogepant
CGRP inhibitor
|
Ubrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine. |
| PC-62994 |
MK-8825
CGRP inhibitor
|
MK-8825 is a highly potent, selective, orally bioavailable CGRP receptor antagonist with Ki of 17 nM for rat CGRP. |
| PC-60031 |
Atogepant
CGRP inhibitor
|
Atogepant (MK-8031) is a potent and selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 2 pM (hCGRP). |
| PC-42296 |
Olcegepant hydrochloride
CGRP inhibitor
|
Olcegepant hydrochloride (BIBN4096BS) is the first small molecule selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 14.4 nM for hCGRP. |
| PC-42294 |
Olcegepant
CGRP antagonist
|
Olcegepant (BIBN-4096, BIBN4096BS) is the first small molecule selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 14.4 nM for hCGRP. |
| PC-45811 |
MK-0974
CGRP inhibitor
|
Telcagepant (MK-0974) is a potent, selective, orally bioavailable CGRP receptor antagonist with Ki of 0.77 nM. |
| PC-42516 |
MK-3207
CGRP inhibitor
|
MK-3207 is a highly potent, selective CGRP receptor antagonist with Ki of 21 pM in in vitro binding assay and IC50 of 0.12 nM in cell-based functional assay. |
| PC-24755 |
Cagrilintide acetate
AMYR/CTR agonist
|
Cagrilintide acetate (AM833) is a long-acting amylin analogue as a nonselective amylin receptor (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist with binding IC50 of 170 and 223 pM, and cAMP EC50 of 348 and 287 pM for hAMY3R and hCTR respectively. |
| PC-24754 |
Cagrilintide
AMYR/CTR agonist
|
Cagrilintide (AM833) is a long-acting amylin analogue as a nonselective amylin receptor (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist with binding IC50 of 170 and 223 pM, and cAMP EC50 of 348 and 287 pM for hAMY3R and hCTR respectively. |
