Chemical Structure : Ubrogepant
CAS No.:
1374248-77-7
Ubrogepant
(MK-1602, MK1602)
Catalog No.: PC-35253Not For Human Use, Lab Use Only.
Ubrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine.
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| 10 mg | $388 | In stock | |
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Purity & Documentation Purity:
>98% (HPLC)
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Biological Activity
Ubrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine.
Physicochemical Properties
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M.Wt
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549.554
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Formula
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C29H26F3N5O3
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20 °C 12 Months; 4°C 6 Months
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- In Solvent
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-80 °C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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(3'S)-1',2',5,7-Tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl]-2'-oxospiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide
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References
1. Li CC, et al. J Clin Pharmacol. 2017 Nov 14. doi: 10.1002/jcph.1021.
2. Holland PR, et al. Neurotherapeutics. 2018 Apr;15(2):304-312.
3. Voss T, et al. Cephalalgia. 2016 Aug;36(9):887-98.
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