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Cat. No. Product Name Information
PC-35367

SG3199

ADC payload

SG3199 (SG-3199) is a PBD dimer warhead component of antibody-drug conjugate (ADC) payload tesirine, demonstrates potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines with mean GI50 of 151.5 pM.
PC-43366

Daunorubicin hydrochloride

Topo II inhibitor

Daunorubicin (RP13057) hydrochloride is potent topoisomerase II (Topo II) inhibitor, interacts with DNA by intercalation and inhibition of macromolecular biosynthesis in cancer cells.
PC-60141

SGD-1882

PBD dimer;Pyrrolobenzodiazepine dimer novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).
PC-60140

D211

A novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).
PC-45714

Mertansine

Mertansine (DM1) is a tubulin inhibitor.
PC-21891

ZD06519

ADC payload

ZD06519 is a novel camptothecin payload for antibody drug conjugates (ADCs) with highp ayload potency (~1 nM).
PC-43367

Daunorubicin

Daunorubicin is potent topoisomerase II (Topo II) inhibitor, interacts with DNA by intercalation and inhibition of macromolecular biosynthesis in cancer cells.
PC-43365

Daun02

Daun02 a prodrug that is converted by β-galactosidase to Daunorubicin, inactivate activated neurons that express both β-galactosidase and Fos, specifically attenuates cocaine-induced locomotor activity, also attenuates cocaine-induced β-galactosidase expression.
PC-70085

Esperamicin A1

Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin.
PC-45656

alpha-Amanitin

α-Amanitin, an 8-Aa cyclic peptide, is an selective inhibitor of RNA polymerase II and III.
PC-45636

Maytansinol

Maytansinol (Ansamitocin P-0) is a microtubule assembly inhibitor.
PC-45655

Calicheamicin

Calicheamicin γ1 is an enediyne antitumor antibiotic that acts by binding to DNA and causes strand scission.

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