Esperamicin A1 |CAS:99674-26-7 Probechem Biochemicals

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Chemical Structure : Esperamicin A1

Esperamicin A1 (BMY 28175)

Catalog No.: PC-70085Not For Human Use, Lab Use Only.

Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin; acts by binding to DNA and causes strand scission; ADC payload used in development of antibody drug conjugates.

Physicochemical Properties

M.Wt	1325.54
Formula	C59H80N4O22S4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Carbamic acid, [8-[[4,6-dideoxy-2-O-[2,4-dideoxy-3-O-methyl-4-[(1-methylethyl)amino]-α-L-threo-pentopyranosyl]-4-[[(2,6-dideoxy-4-S-methyl-4-thio-β-D-ribo-hexopyranosyl)oxy]amino]-β-D-glucopyranosyl]oxy]-12-[[2,6-dideoxy-3-O-[4,5-dimethoxy-2-[(2-methoxy-1

References

1. Lam KS, et al. J Antibiot (Tokyo). 1995 Dec;48(12):1497-501.

2. Biggins JB, et al. Science. 2003 Sep 12;301(5639):1537-41.

3. Kumar RA, et al. J Mol Biol. 1997 Jan 17;265(2):173-86.

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Esperamicin A1 (BMY 28175)

Biological Activity

Physicochemical Properties

References

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