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Esperamicin A1

Chemical Structure : Esperamicin A1

CAS No.: 99674-26-7

Esperamicin A1 (BMY 28175)

Catalog No.: PC-70085Not For Human Use, Lab Use Only.

Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin, acts by binding to DNA and causes strand scission, an ADC payload used in development of antibody drug conjugates.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin, acts by binding to DNA and causes strand scission, an ADC payload used in development of antibody drug conjugates.

    Physicochemical Properties

    M.Wt 1325.54
    Formula C59H80N4O22S4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Carbamic acid, [8-[[4,6-dideoxy-2-O-[2,4-dideoxy-3-O-methyl-4-[(1-methylethyl)amino]-α-L-threo-pentopyranosyl]-4-[[(2,6-dideoxy-4-S-methyl-4-thio-β-D-ribo-hexopyranosyl)oxy]amino]-β-D-glucopyranosyl]oxy]-12-[[2,6-dideoxy-3-O-[4,5-dimethoxy-2-[(2-methoxy-1

    References

    1. Lam KS, et al. J Antibiot (Tokyo). 1995 Dec;48(12):1497-501.

    2. Biggins JB, et al. Science. 2003 Sep 12;301(5639):1537-41.

    3. Kumar RA, et al. J Mol Biol. 1997 Jan 17;265(2):173-86.

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