| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-49111 |
SU0448
|
|
SU0448 is a specific, cell-permeable small molecule activator of the DNA repair enzyme Human MutT Homolog 1 (MTH1) with AC50 value of 5.5 uM, inhibits cell viability of HCC1806 cells with IC50 of 36.1 uM. |
| PC-35301 |
AOH1160
|
2089314-57-6 |
AOH1160 (AOH-1160) is a potent, first-in-class, orally available small molecule inhibitor of Proliferating cell nuclear antigen (PCNA). |
| PC-63192 |
IACS-4619
|
1884209-98-6 |
IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.2 nM. |
| PC-62706 |
Karonudib
|
|
Karonudib (TH1579) is an analogue of TH588, a potent, selective MTH1 inhibitor with good oral availability and demonstrates excellent pharmacokinetic and anti-cancer properties in vivo.. |
| PC-62705 |
IACS-4759
|
1884209-99-7 |
IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.6 nM. |
| PC-62517 |
TH 5427
|
2253744-56-6 |
TH 5427 (TH5427) is a potent, small molecule NUDT5 (NUDIX5) inhibitor with IC50 of 29 nM, 690-fold selectivity for NUDT5 over MTH1 (NUDT1) in vitro. |
| PC-62268 |
YU 238259
|
1943733-16-1 |
YU 238259 is a novel DNA double-strand break repair inhibitor that exhibits potent synthetic lethality in the setting of DNA damage response and DNA repair defects. |
