Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

You are here:Home-Chemical Inhibitors & Agonists-Cell Cycle/DNA Damage-DNA Repair Protein -MUS81 inhibitor 23
MUS81 inhibitor 23

Chemical Structure : MUS81 inhibitor 23

CAS No.:

MUS81 inhibitor 23

Catalog No.: PC-22696Not For Human Use, Lab Use Only.

MUS81 inhibitor 23 is a small molecule inhibitor of DNA repair endonuclease Mus81 with IC50 of 0.32 uM and SPR Kd of 0.67 uM (MUS81-EME1).

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MUS81 inhibitor 23 is a small molecule inhibitor of DNA repair endonuclease Mus81 with IC50 of 0.32 uM and SPR Kd of 0.67 uM (MUS81-EME1).
The Mus81 endonuclease resolves recombination intermediates and mediates cellular responses to exogenous replicative stress.

Physicochemical Properties

M.Wt 419.44
Formula C23H21N3O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-hydroxy-4-oxo-1-(4'-(piperazine-1-carbonyl)-[1,1'-biphenyl]-4-yl)-1,4-dihydropyridine-3-carboxylic acid

References

1. Collie GW, et al. ACS Med Chem Lett. 2024 Jun 7;15(7):1151-1158.

2. Haiqing Fu, et al. Nat Commun. 2015 Apr 16:6:6746.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: