| Cat. No. |
Product Name |
Information |
| PC-20115 |
ET516
|
ET516 is a potent androgen receptor liquid-liquid phase separation (AR LLPS) inhibitor, specifically disrupts AR condensates, effectively suppresses AR transcriptional activity and inhibits the proliferation and tumor growth of prostate cancer cells expressing AR-resistant mutants. |
| PC-49597 |
UT-143
|
UT-143 (UT143) is a small-molecule selective androgen receptor (AR) irreversible covalent antagonist, covalently and selectively bind to C406 and C327 in the AF-1 region of AR. |
| PC-49173 |
JJ-450
|
JJ-450 is a novel analogue of IMTPPE and direct and specific inhibitor of androgen receptor (AR) transcriptional activity, blocks AR recruitment to androgen-responsive elements and suppresses AR target gene expression. |
| PC-72753 |
VPC-13789
|
VPC-13789 (VPC13789) is a potent, selective, orally available inhibitor of androgen receptor binding function-3 (BF3) site with IC50 of 0.19 uM. |
| PC-72511 |
JNJ-63576253
|
JNJ-63576253 (TRC-253, JNJ63576253) is a next-generation, potent, selective androgen receptor (AR) antagonist (inhibitor) against wild-type AR (IC50=6.9 nM), AR F877L and other clinically detected ligand binding domain (LBD) point mutations. |
| PC-35680 |
KCI807
|
KCI807 (KCI-807) is a small molecule that selectively disrupts ELK1-dependent promoter activation by wild-type and variant androgen receptors (IC50=0.53 uM) without interfering with ELK1 activation by ERK. |
| PC-43500 |
Cortexolone 17 alpha-propionate
|
Cortexolone 17 alpha-propionate (CB-03-01, Clascoterone) is a topical and peripherally selective androgen antagonist, displays a strong local antiandrogenic activity in hamster's flank organ test, does not exhibit antiandrogenic activity after subcutaneous injection in vivo. |
