| Cat. No. |
Product Name |
Information |
| PC-22037 |
Bicalutamide
AR antagonist
|
Bicalutamide (ICI 176,334) is an orally active non-steroidal androgen receptor (AR) antagonist for treatment of prostate cancer. |
| PC-21578 |
AR NTD inhibitor 16
AR NTD inhibitor
|
AR NTD inhibitor 16 is a small molecule inhibitor of androgen receptor N-terminal domain (AR NTD) with IC50 of 0.12 uM in VCaP cell-based GRE2-luciferase reporter gene assays. |
| PC-21406 |
UT-155
AR inhibitor
|
UT-155 is a potent and selective androgen receptor (AR) degrader (SARD), binds to AR-LBD (Ki=267 nM), degrades and inhibits AR and AR splice variants (AR-SVs), including AR-V7. |
| PC-21405 |
UT-34
AR antagonist, SARD
|
UT-34 is a potent, second-generation androgen receptor (AR) pan antagonist, degrades enzalutamide-sensitive and -resistant ARs and AR splice variants (AR-SVs). |
| PC-21404 |
UT-105
AR inhibitor
|
UT-105 is a small-molecule, irreversible, selective androgen receptor (AR) degrader (SARD) and irreversible inhibitor, binds to AR N-terminal domain (NTD) and inhibits both the AR and AR splice variants (AR-SVs). |
| PC-49597A |
UT-215
AR antagonist
|
UT-215 (UT215) is a small-molecule selective androgen receptor (AR) irreversible covalent antagonist, covalently and selectively bind to C406 and C327 in the AF-1 region of AR. |
| PC-20797 |
M17-B15
AR inhibitor
|
M17-B15 is a potent, specific small molecule inhibitor of androgen receptor (AR) targeting the dimer interface pocket (DIP), inhibits AR transcriptional inhibition with IC50 of 0.03 uM. |
| PC-20758 |
SC428
AR NTD inhibitor
|
SC428 (SC-428) is a small molecule androgen receptor (AR) signaling inhibitor, directly binds to the AR N-terminal domain (NTD) and exhibits pan-AR inhibitory effect. |
| PC-20115 |
ET516
AR inhibitor
|
ET516 is a potent androgen receptor liquid-liquid phase separation (AR LLPS) inhibitor, specifically disrupts AR condensates, effectively suppresses AR transcriptional activity and inhibits the proliferation and tumor growth of prostate cancer cells expressing AR-resistant mutants. |
| PC-20039 |
Gumelutamide
AR inhibitor
|
Gumelutamide (TAS3681) is a potent, selective androgen receptor (AR) pure antagonist with Ki of 7.39 and 23.8 nM for WT AR and AR T878A mutant respectively, inhibits AR transcriptional activity and downregulates AR-full length (AR-FL) and AR-Vs. |
| PC-20032 |
Faznolutamide
AR inhibitor
|
Faznolutamide is a potent, selective androgen receptor (AR) antagonist. |
| PC-49722 |
Vosilasarm
SARM
|
Vosilasarm (RAD-140, EP0062) is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM), shows excellent affinity for the androgen receptor (Ki=7 nM). |
