| Cat. No. |
Product Name |
Information |
| PC-73220 |
Pyrilutamide
AR antagonist
|
Pyrilutamide (KX826) is an androgen receptor (AR) antagonist and a potential first-in-class topical drug for the treatment of androgenetic alopecia (AGA) and acne vulgaris. |
| PC-73182 |
Apalutamide
AR antagonist
|
Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist with binding IC50 of 16 nM. |
| PC-72753 |
VPC-13789
Androgen receptor inhibitor
|
VPC-13789 (VPC13789) is a potent, selective, orally available inhibitor of androgen receptor binding function-3 (BF3) site with IC50 of 0.19 uM. |
| PC-72512 |
JNJ-pan-AR
AR inhibitor
|
JNJ-pan-AR is a highly potent, selective antagonist of androgen receptor (AR) wild-type and F877L mutant for the treatment of the F877L mutant and wild-type CRPC. |
| PC-72511 |
JNJ-63576253
AR inhibitor
|
JNJ-63576253 (TRC-253, JNJ63576253) is a next-generation, potent, selective androgen receptor (AR) antagonist (inhibitor) against wild-type AR (IC50=6.9 nM), AR F877L and other clinically detected ligand binding domain (LBD) point mutations. |
| PC-35866 |
IMTPPE
AR inhibitor
|
IMTPPE (SID 3712502) is a novel small molecule capable of inhibiting androgen receptor (AR) transcriptional activity (IC50=1 uM) and protein level in C4-2 prostate cancer cells. |
| PC-35680 |
KCI807
Androgen Receptor inhibitor
|
KCI807 (KCI-807) is a small molecule that selectively disrupts ELK1-dependent promoter activation by wild-type and variant androgen receptors (IC50=0.53 uM) without interfering with ELK1 activation by ERK. |
| PC-35346 |
RD162
AR antagonist
|
RD162 is a second-generation, orally available antiandrogen that binds to androgen receptor (AR) with IC50 of 30.9 nM. |
| PC-35143 |
LGD-2226
SARM
|
LGD-2226 (LGD2226) is an orally active, selective androgen receptor modulator (SARM) with binding Ki of 1 nM, >1000-fold selectivity over GR,PR, MR and ER. |
| PC-35133 |
LY305
SARM
|
LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM, demonstrates potent agonist activity in the aforementioned C2C12 cellular assay (EC50=0.499 nM). |
| PC-35003 |
BAY 1024767
AR antagonist
|
BAY 1024767 (BAY1024767) is a higly potent antagonist of androgen receptor (AR) wild-type (IC50=46 nM) and mutant forms located in the AR ligand-binding domain (LBD). |
| PC-43500 |
Cortexolone 17 alpha-propionate
|
Cortexolone 17 alpha-propionate (CB-03-01, Clascoterone) is a topical and peripherally selective androgen antagonist, displays a strong local antiandrogenic activity in hamster's flank organ test, does not exhibit antiandrogenic activity after subcutaneous injection in vivo. |
