| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-63311 |
BRD0705
|
2056261-41-5 |
BRD0705 is a potent, paralog-selective GSK3α inhibitor with IC50 of 66 nM, 8-fold selectivity over GSK3β (IC50=515 nM). |
| PC-63153 |
1-Azakenpaullone
|
676596-65-9 |
1-Azakenpaullone is an analog of kenpaullone and is a potent, selective GSK3β inhibitor with IC50 of 18 nM, weakly inhibits CDK1/cyclin B and CDK5/p25 (IC50=2.0 and 4.2 uM). |
| PC-60431 |
9-ING-41
|
1034895-42-5 |
Elraglusib (9-ING-41) is a novel potent, selective GSK-3β inhibitor with IC50 of 0.7 uM. |
| PC-42428 |
CHIR-99021
|
252917-06-9 |
Laduviglusib (CHIR-99021, CT99021) is a potent, specific GSK-3 inhibitor with IC50 of 5 nM and 10 nM for GSK3β and GSK3α, respectively. |
| PC-45724 |
Indirubin-3|-monoxime
|
160807-49-8 |
A potent GSK3β inhibitor with IC50 of 22 nM. |
| PC-20114 |
GSK-3β inhibitor 47
|
2227316-74-5 |
GSK-3β inhibitor 47 is a potent, selective, brain-penetrant, orally bioavailable GSK-3β inhibitor with IC50 of 0.73 nM, inhibits phosphorylated tau with cell IC50 of 58 nM. |
| PC-49290 |
Tideglusib
|
865854-05-3 |
Tideglusib (NP031112, NP-12) is a potent and irreversible small molecule glycogen synthase kinase 3 (GSK-3) inhibitor with IC50 of 60 nM. |
