| Cat. No. |
Product Name |
Information |
| PC-25724 |
Pentagalloylglucose
TRMT61A inhibitor
|
Pentagalloylglucose is an orally active gallic tannin compound, induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway, inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids, also is a specific TRMT61A inhibitor. |
| PC-25343 |
GSK-3β inhibitor G3I
GSK-3β inhibitor
|
GSK-3β inhibitor G3I is a specific GSK-3β inhibitor, inhibits nitric oxide (NO) production in LPS-stimulated macrophages with IC50 of 3.65 uM. |
| PC-22892 |
BRD0320
GSK3α/β inhibitor
|
BRD0320 is a potent, dual inhibitor of GSK3α/β with Kd of 1.2/1.9 uM respectively. |
| PC-22738 |
Iodobikinin
GSK3-like kinase BIN2 inhibitor
|
Iodobikinin is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor, binds and inhibits GSK3-like kinase BIN2. |
| PC-22537 |
GSK3β inhibitor MJ34
GSK3β inhibitor
|
GSK3β inhibitor MJ34 (ISO-1479) is a potent, GSK3β selective inhibitor with IC50 of 15.4 nM, significantly reduces growth and survival of human mutant KRas dependent pancreatic tumors. |