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Request The Product List ofGSK-3 GSK-3

Cat. No. Product Name Information
PC-49262

SB415286

GSK-3 inhibitor

SB-415286 (SB415286) is a potent, selective, ATP competitive small molecule inhibitor of GSK-3alpha with Ki of 31 nM, inhibits GSK-3beta with similar potency.
PC-38653

ARN25068

GSK-3β/FYN/DYRK1A inhibitor

ARN25068 is a highly potent, triple GSK-3β/FYN/DYRK1A inhibitor with sub-micromolar potency, reduces the extent of tau phosphorylation in Tau0N4R-TM-tGFP U2OS cell line.
PC-38527

GSK-3 Inhibitor XIII

GSK-3 inhibitor

GSK-3 Inhibitor XIII is a potent and ATP-binding site inhibitor of GSK-3.
PC-63357

MMBO

MMBO is a potent, highly selective, brain penetrant, orally active inhibitor of GSK-3 with IC50 of 37 and 53 nM for GSK-3α and GSK-3β, respectively.
PC-63312

BRD3731

BRD3731 is a potent, selective GSK3β inhibitor with IC50 of 15 nM, 14-fold selectivity for GSK3β over GSK3α (IC50=215 nM).
PC-63239

Methyliodobikinin

Methyliodobikinin is a potent bikinin-like inhibitor targeting GSK3/Shaggy-like kinase, shows improved cell permeability, highly potent in vivo although it had lower activity in vitro.
PC-43377

CHIR-98014

CHIR-98014 is a potent, selective glycogen synthase kinase 3 (GSK-3) withIC50 of 0.65 and 0.58 nM for GSK-3α and GSK-3β, respectively.
PC-43092

Bikinin

Bikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor, binds and inhibits Arabidopsis thaliana GSK3-like kinases.
PC-42955

IM-12

IM-12 is a novel potent GSK-3β inhibitor with IC50 of 53 nM, significantly increases the β-catenin level and activates canonical Wnt signalling.
PC-63152

Cazpaullone

Cazpaullone (9-Cyano-1-azapaullone) is a derivative of 1-Azakenpaullone, a potent, selective GSK3β inhibitor with IC50 of 8 nM, weakly inhibits CDK1/cyclin B and CDK5/p25 (IC50=0.5 and 0.3 uM).
PC-62878

BRD1172

BRD1172 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 3 nM/10 nM for GSK3α/GSK3β, respectively..
PC-62876

BRD0209

BRD0209 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 19 nM/5 nM for GSK3α/GSK3β respectively.

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