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Chemical Structure : IM-12
CAS No.: 1129669-05-1
Catalog No.: PC-42955Not For Human Use, Lab Use Only.
IM-12 is a novel potent GSK-3β inhibitor with IC50 of 53 nM, significantly increases the β-catenin level and activates canonical Wnt signalling.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $168 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | $408 | In stock | |
| 500 mg | Get quote |
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IM-12 is a novel potent GSK-3β inhibitor with IC50 of 53 nM, significantly increases the β-catenin level and activates canonical Wnt signalling; attenuates cell proliferation of ReNcell VM cells, induces nuclear accumulation of beta-catenin.
| M.Wt | 377.4115 | |
| Formula | C22H20FN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 54.9 mg/mL |
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| Chemical Name/SMILES |
1H-Pyrrole-2,5-dione, 3-[[2-(4-fluorophenyl)ethyl]amino]-1-methyl-4-(2-methyl-1H-indol-3-yl)- |
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1. Schmöle AC, et al. Bioorg Med Chem. 2010 Sep 15;18(18):6785-95.
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