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kb-NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM.


CRT0066101 (CRT-0066101) is a potent, specific, orally active pan-PKD (protein kinase D) inhibitor with biochemical IC50 of 1, 2.5 and 2 nM for PKD1, 2, and 3 respectively.

PKD inhibitor CRT5

CRT5 (PKD inhibitor CRT5) is a potent, selective pyrazine benzamide inhibitor of PKD (protein kinase D), inhibits peptide substrate phosphorylation with IC50 of 1, 2 and 1.5 nM for PKD1, PKD2 and PKD3, respectively.


The first potent and selective cell-active pan-PKD inhibitor with IC50s of 182/280/227 nM for PKD1/2/3 respectively.

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