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Cat. No. Product Name Information
PC-49053

IGUANA-1

IGUANA-1 is a potent, isoform-selective inhibitor of aldehyde dehydrogenase ALDH1B1, exhibits proteome-wide target specificity, and selectively blocks the growth of colon cancer spheroids and organoids.
PC-72799

MCI-INI-3

MCI-INI-3 is a potent, selective, competitive inhibitor of ALDH1A3 (Ki=0.55 uM, shows poor inhibitory effect on the structurally related isoform ALDH1A1 (>140-fold selectivity).
PC-72688

Dichloro-all-trans-retinone

Dichloro-all-trans-retinone (DAR) is an irreversible inhibitor of retinaldehyde dehydrogenase (RALDH/ALDH1A) with IC50 of 434/55/161 nM for RALDH1/RALDH2/RALDH3.
PC-38166

KS100

ALDH inhibitor KS100 (KS100) is a novel, potent, multi-isoform ALDH inhibitor with IC50 of 207/1410/240 nM for ALDH1A1/ALDH2/ALDH3A1, respectively.
PC-35126

NCT-505

NCT-505 (NCT505) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases.
PC-61351

DIMATE

DIMATE is a novel irreversible, competitive, isoform-specific ALDH1 inhibitor, displays cytotoxic activity on human AML cell lines with IC50 of 1-15 uM.
PC-61349

CVT-10216

CVT-10216 (CVT10216) is a potent, highly selective, reversible inhibitor of ALDH2 with IC50 of 29 nM, shows no significant inhibition for ALDH1 (IC50=1,300 nM).

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