| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-72799 |
MCI-INI-3
|
1011366-31-6 |
MCI-INI-3 is a potent, selective, competitive inhibitor of ALDH1A3 (Ki=0.55 uM, shows poor inhibitory effect on the structurally related isoform ALDH1A1 (>140-fold selectivity). |
| PC-35126 |
NCT-505
|
2231079-75-5 |
NCT-505 (NCT505) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases. |
| PC-61351 |
DIMATE
|
350229-29-7 |
DIMATE is a novel irreversible, competitive, isoform-specific ALDH1 inhibitor, displays cytotoxic activity on human AML cell lines with IC50 of 1-15 uM. |
| PC-45551 |
NCT-501
|
1802088-50-1 |
NCT-501 (NCT501) is a potent and highly selective inhibitor of ALDH1A1 with IC50 of 40 nM for hALDH1A1. |
| PC-20140 |
STA-55
|
2451093-96-0 |
STA-55 is a broad-spectrum activity-based probe of aldehyde dehydrogenase family, can be used to identify therapy resistance biomarkers in cancer and to validate target engagement of ALDH drug candidates. |
| PC-20139 |
LEI-945
|
2582758-03-8 |
LEI-945 (LEI 945) is a first-in-class probe that enables profiling retinaldehyde dehydrogenases (ALDHs) in cancer cells. |
| PC-49239 |
ALDH1A1 inhibitor CM37
|
896795-60-1 |
ALDH1A1 inhibitor CM37 is a selective and competitive inhibitor of ALDH1A1 with Ki of 300 nM, shows minimal inhibitory effects for ALDH1A2, ALDH1A3, ALDH2, or ALDH3A1 at 20 uM. |
