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ALD1A3 inhibitor CB7

Chemical Structure : ALD1A3 inhibitor CB7

CAS No.: 324777-01-7

ALD1A3 inhibitor CB7

Catalog No.: PC-20207Not For Human Use, Lab Use Only.

ALD1A3 inhibitor CB7 is a highly selective inhibitor of ALDH3A1 with IC50 of 0.2 uM, does not inhibit ALDH1A1, ALDH1A2, ALDH1A3, ALDH1B1, or ALDH2 activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ALD1A3 inhibitor CB7 is a highly selective inhibitor of ALDH3A1 with IC50 of 0.2 uM, does not inhibit ALDH1A1, ALDH1A2, ALDH1A3, ALDH1B1, or ALDH2 activity.
CB7 binds to the aldehyde binding pocket of ALDH3A1.

Physicochemical Properties

M.Wt 290.31
Formula C14H11FN2O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-[(4-fluorophenyl)sulfonyl]-2-methyl-1H-benzimidazole

References

1. Parajuli B, et al. J Med Chem. 2014 Jan 23;57(2):449-61.

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