| Cat. No. |
Product Name |
Information |
| PC-21250 |
AD-5591
ALDH2 activator
|
AD-5591 (AD5591) is a potent, selective, new generation small molecule ALDH2 activator, has the improved biological activities and pharmacological properties compared to Alda-1. |
| PC-20212 |
KOTX1
ALDH1A3 inhibitor
|
KOTX1 is a potent, selective and reversible ALDH1A3 inhibitor with IC50 of 5.14 nM by Aldefluor assay in A375 cells. |
| PC-20210 |
ER-001135935
ALDH1A3 inhibitor
|
ER-001135935 is a potent selective inhibitor of aldehyde dehydrogenase family 1 member A3 (ALDH1A3) with IC50 of 64 nM, Ki value of 106 nM. |
| PC-20209 |
ALDH1A3 inhibitor NR6
ALDH1A3 inhibitor
|
ALDH1A3 inhibitor NR6 is a specific ALDH1A3 inhibitor with IC50 of 5.3 uM and Ki of 3.7 uM, high selective over ALDH1A1 and ALDH1A2. |
| PC-20208 |
ALD1A3 inhibitor MF-7
ALDH1A3 inhibitor
|
ALD1A3 inhibitor MF-7 is a specific ALD1A3 inhibitor with IC50 of 22.8 uM on recombinant human ALDH1A3. |
| PC-20207 |
ALD1A3 inhibitor CB7
ALDH1A3 inhibitor
|
ALD1A3 inhibitor CB7 is a highly selective inhibitor of ALDH3A1 with IC50 of 0.2 uM, does not inhibit ALDH1A1, ALDH1A2, ALDH1A3, ALDH1B1, or ALDH2 activity. |
| PC-20206 |
ALD1A3 inhibitor CB29
ALDH1A3 inhibitor
|
ALD1A3 inhibitor CB29 is a selective small molecule inhibitor of ALDH3A1 with IC50 of 16 uM, and Ki value of 4.7 uM. |
| PC-20201 |
ALDH1A1 inhibitor N42
ALDH1A1 inhibitor
|
ALDH1A1 inhibitor N42 (FSI-TN42) is a potent, specific and orally bioavailable ALDH1A1 inhibitor with IC50 of 23 nM, 800-fold selectivity over ALDH1A2 (IC50=18 uM). |
| PC-20140 |
STA-55
ALDHs chemical probe
|
STA-55 is a broad-spectrum activity-based probe of aldehyde dehydrogenase family (ALDHs), can be used to identify therapy resistance biomarkers in cancer and to validate target engagement of ALDH drug candidates. |
| PC-20139 |
LEI-945
ALDHs chemical probe
|
LEI-945 (LEI 945) is a first-in-class probe that enables profiling retinaldehyde dehydrogenases (ALDHs) in cancer cells. |
| PC-49239 |
ALDH1A1 inhibitor CM37
ALDH1A1 inhibitor
|
ALDH1A1 inhibitor CM37 is a selective and competitive inhibitor of ALDH1A1 with Ki of 300 nM, shows minimal inhibitory effects for ALDH1A2, ALDH1A3, ALDH2, or ALDH3A1 at 20 uM. |
| PC-49238 |
ALDH1A1 inhibitor 974
ALDH1A1 inhibitor
|
ALDH1A1 inhibitor 974 (Compound 974) is a first-in-class, highly potent and specific ALDH1A1 inhibitor with IC50 of 470 nM, suppresses chemotherapy-induced senescence as well as stemness. |
