Catalog No.: PC-27271Not For Human Use, Lab Use Only.
Daidzin is a 7-glucoside of 4',7-dihydroxyisoflavone and a potent, selective, competitive inhibitor of human mitochondrial aldehyde dehydrogenase (ALDH-I, ALDH2) with Ki of 40 nM, >1000-fold selective over cytosolic aldehyde dehydrogenase isozyme (ALDH-II).
Daidzin is a 7-glucoside of 4',7-dihydroxyisoflavone and a potent, selective, competitive inhibitor of human mitochondrial aldehyde dehydrogenase (ALDH-I, ALDH2) with Ki of 40 nM, >1000-fold selective over cytosolic aldehyde dehydrogenase isozyme (ALDH-II). Daidzin does not inhibit human class I, II, or III alcohol dehydrogenases. Daidzin can suppress ethanol intake of this species without blocking acetaldehyde metabolism. Daidzin suppresses hamster ethanol intake also inhibit 5-HIAA and DOPAC formation. Daidzin shows effective anti-inflammatory and antioxidant potential.
