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Cat. No. Product Name Information
PC-21996

beta-Amyloid (42-1) human

β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42). β-Amyloid (42-1), human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
PC-20458

CNB-001

Aβ inhibitor

CNB-001 is a pyrazole derivative of curcumin with neuroprotective properties, inhibits extracellular Aβ toxicity in hippocampal neurons with EC50 of 400 nM.
PC-38734

Senile plaques (SPs) probe BSB

Aβ-specific ligand

Senile plaques (SPs) probe BSB is a chemical probe that can detect accumulation of Aβ in senile plaques (SPs) in vivo, exhibits high binding affinity for Aβ aggregates in vitro (Ki=0.4 uM).
PC-38480

TAE-1

Amyloid-beta modulator

TAE-1 is a sym-triazine-derived aggregation modulator, destabilizes Aβ1-42 assembly and inhibits amyloid-β fibril formation, also inhibits acetylcholinesterase (AChE) activity in SH-SY5Y neuronal cells.
PC-38408

ALI6

Aβ-LilrB2 inhibitor

ALI6 (Fluspirilene, Aβ-LilrB2 interaction inhibitor 6) is a small molecule Aβ-LilrB2 interaction inhibitor with Ki of 320 nM, blocks LilrB2 induced cell attachment and inhibit toxicity of Aβ.
PC-73428

Minzasolmin

α-synuclein inhibitor

Minzasolmin (UCB0599) is an orally bioavailable and brain-penetrant small molecule alpha-synuclein (ASYN) misfolding inhibitor, UCB0599 is a single enantiomer of NPT200-11 (Cat#PC-35764).
PC-73339

Ro 90-7501

Aβ42 inhibitor

Ro 90-7501 is a prototypic inhibitor for Abeta42 (Aβ42) fibril formation, reduces Aβ42-induced cytotoxicity (EC50=2 uM), also enhances TLR3 and RLR agonist induced antiviral response.
PC-73134

Synucleozid

α-synuclein inhibitor

Synucleozid (NSC 377363) is a small molecule that targets the IRE structure and inhibits SNCA gene translation in cells, directly targets the α-synuclein mRNA 5'UTR at the designed site.
PC-73121

anle145c

Amyloid aggregation inhibitor

anle145c is a small molecule inhibitor of amyloid aggregation and formation, inhibits human islet amyloid polypeptide (hIAPP)-induced death of INS-1E cells.
PC-38109

YX-I-1

hIAPP modulator

YX-I-1 is a small-molecule modulator of human islet amyloid polypeptide (hIAPP) assembly, specifically inhibits amyloid formation.
PC-38108

YX-A-1

hIAPP modulator

YX-A-1 is a small-molecule modulator of human islet amyloid polypeptide (hIAPP) assembly, specifically enhances amyloid formation.
PC-35764

NPT200-11

alpha-synuclein inhibitor

NPT200-11 is an orally bioavailable and brain penetrating alpha-synuclein (ASYN) misfolding and aggregation inhibitor.

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