Cat. No. |
Product Name |
CAS No. |
Information |
PC-62602 |
ALZ-801
|
1034190-08-3 |
ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate, a small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor for the treatment of Alzheimer's disease.. |
PC-45445 |
ARN-2966
|
102212-26-0 |
ARN-2966 is a potent, BBB penetrant post-transcriptional modulator of APP expression in transfected CHO cells that produce amyloid precursor protein (APP). |
PC-45627 |
FPS-ZM1
|
945714-67-0 |
FPS-ZM1 is a high-affinity RAGE-specific inhibitor. |
PC-38734 |
Senile plaques (SPs) probe BSB
|
291766-06-8 |
Senile plaques (SPs) probe BSB is a chemical probe that can detect accumulation of Aβ in senile plaques (SPs) in vivo, exhibits high binding affinity for Aβ aggregates in vitro (Ki=0.4 uM). |
PC-38480 |
TAE-1
|
1414469-59-2 |
TAE-1 is a sym-triazine-derived aggregation modulator, destabilizes Aβ1-42 assembly and inhibits amyloid-β fibril formation, also inhibits acetylcholinesterase (AChE) activity in SH-SY5Y neuronal cells. |
PC-38408 |
ALI6
|
1841-19-6 |
ALI6 (Fluspirilene, Aβ-LilrB2 interaction inhibitor 6) is a small molecule Aβ-LilrB2 interaction inhibitor with Ki of 320 nM, blocks LilrB2 induced cell attachment and inhibit toxicity of Aβ. |
PC-73339 |
Ro 90-7501
|
293762-45-5 |
Ro 90-7501 is a prototypic inhibitor for Abeta42 (Aβ42) fibril formation, reduces Aβ42-induced cytotoxicity (EC50=2 uM), also enhances TLR3 and RLR agonist induced antiviral response. |