Cat. No. |
Product Name |
Information |
PC-23221 |
TZ095
Aβ fluorescent probe
|
TZ095 is a coumarin-based Aβ fluorescent probe for precise Aβ detection, exhibits remarkable affinity with Aβ aggregates (Kd = 81.54 nM for oligomers; Kd = 66.70 nM for fibril) and substantial fluorescence enhancement (F/F0 = 44). |
PC-23194 |
anti-Aβ molecule M30
Aβ inhibitor
|
anti-Aβ molecule M30 is a small anti-Aβ molecule, binds to Aβ1-42 tetramer through hydrogen bonds resulting in a conformational stable Aβ1-42-M30 complex, prevent synaptotocity, improving AD-affected mice memory. |
PC-23152 |
wact-190
Amyloid inhibitor
|
wact-190 is a small molecule inhibitor of amyloid aggregation. |
PC-22533 |
C05-05
α-synuclein imaging agent
|
C05-05 is a small molecule imaging agent for α-synuclein pathologies for in vivo optical visualization of α-synuclein inclusions and tracking of pathological α-synuclein propagation. |
PC-22406 |
ROF2
Amyloid probe
|
ROF2 is an aggregation-induced emission (AIE) small molecule, functionalities as an amyloid probe and a screening tool for amyloid inhibitors using different biophysical, cellular, and worm assays. |
PC-21685 |
SRI-42667
Tau-SH3 inhibitor
|
SRI-42667 is a selective small-molecule Tau-SH3 interaction inhibitor with IC50 of 0.91 uM (Tau-FynSH3 interaction), prevents amyloid-β toxicity and network hyperexcitability. |
PC-21679 |
Synucleozid-2.0
α-synuclein inhibitor
|
Synucleozid-2.0 is a drug-like small molecule that decreases α-synuclein levels by inhibiting ribosomes from assembling onto SNCA mRNA. |
PC-21401 |
DDQ
Aβ-Drp1 inhibitor
|
DDQ is a small molecule inhibitor of binding sites of Amyloid beta (Aβ) and Drp1, reduces interaction between Aβ and Drp1, shows anti-aging effects. |
PC-20803 |
MeSC-04
α-synuclein inhibitor
|
MeSC-04 is a potent α-Syn amyloid formation inhibitor, reduces the number and size of amyloid fibrils in vitro. |