Chemical Structure : Licochalcone B
CAS No.: 58749-23-8
Catalog No.: PC-23579Not For Human Use, Lab Use Only.
Licochalcone B is an extract from the root of Glycyrrhiza uralensis, inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduces metal-induced Aβ42 aggregation through chelating metal ions.
Packing | Price | Stock | Quantity |
---|---|---|---|
5 mg | $178 | In stock | |
10 mg | $288 | In stock | |
25 mg | $498 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Licochalcone B is an extract from the root of Glycyrrhiza uralensis, inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduces metal-induced Aβ42 aggregation through chelating metal ions.
Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction.
Licochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway.
Licochalcone B inhibits growth and induces apoptosis of NSCLC cells.
M.Wt | 286.28 | |
Formula | C16H14O5 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
(E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one |
1. Cao Y, et al. Nat Prod Res. 2018 Oct 22:1-4.
2. Jun-ichi Furusawa, et al. Int Immunopharmacol. 2009 Apr;9(4):499-507.
3. Ha-Na Oh, et al. Phytomedicine. 2019 Oct;63:153014.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright