| Cat. No. |
Product Name |
Information |
| PC-24171 |
Prifetrastat
KAT6 inhibitor
|
Prifetrastat (PF-07248144) is a potent, selective histone acetyltransferase KAT6 (KAT6A/6B) inhibitor. |
| PC-23297 |
BAY-184
KAT6A/B inhibitor
|
BAY-184 is a potent, selective and in vivo-active KAT6A/B inhibitor with IC50 of 71/83 nM respectively. |
| PC-20778 |
C646
p300 inhibitor
|
C646 is a selective, competitive histone acetyltransferase (HAT) p300 inhibitor with Ki of 400 nM, less potent for other acetyltransferases. |
| PC-20777 |
MC4171
KAT8 inhibitor
|
MC4171 (KAT8 inhibitor 34) is a first-in-class, selective and reversible lysine acetyltransferase KAT8 inhibitor with IC50 of 8.1 uM and SPR Kd of 2.04 uM. |
| PC-49533 |
JG-2016
HAT1 inhibitor
|
JG-2016 is a small molecule inhibitor of histone acetyltransferase 1 (HAT1) with IC50 of 14.8 uM in the HAT1 acetylation assays. |
| PC-49530 |
DS-9300
EP300/CBP inhibitor
|
DS-9300 (DS9300) is a highly potent, selective and orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with IC50 of 28 nM, inhibits cellular acetylation of histone H3K27 (H3K27Ac) with IC50 of 54 nM. |
| PC-38649 |
DS17701585
EP300/CBP inhibitor
|
DS17701585 is a novel potent, highly selective EP300/CBP histone acetyltransferase inhibitor with IC50 of 0.15 uM. |
| PC-73089 |
iP300w
p300/CBP inhibitor
|
iP300w (CP-C27) is a potent, selective, orally bioavailable inhibitor of p300/CBP histone acetyltransferases with IC50 of 19 nM (p300), H3K27Ac EC50 of 5 nM, does not inhibitor other HATs. |
| PC-72790 |
IMP-1575
HHAT inhibitor
|
IMP-1575 (IMP1575) is a potent, selective Hedgehog acyltransferase (HHAT) inhibitor with Ki/IC50 of 38 nM/0.75 uM (Acyl-cLIP assay). |
| PC-72712 |
ENL YEATS Domain inhibitor 7
ENL YEATS Domain inhibitor
|
ENL YEATS Domain inhibitor 7 is a selective, small molecule inhibitor of ENL YEATS Domain with IC50 of 0.62 uM in inhibiting the ENL-acetyl-H3 interaction. |
| PC-72392 |
PF-9363
KAT6 inhibitor
|
PF-9363 (CTx-648) is a first-in-class, potent and selective KAT6A/6B inhibitor with Ki of 0.41 nM and 1.2 nM for KAT6A and KAT6B, respectively. |
| PC-72364 |
Cholera Toxin B subunit
p300 activator
|
Cholera Toxin B subunit (CTB) is a small molecule activator of p300 HAT enzyme, stimulats the expression of p300. |
