| Cat. No. |
Product Name |
Information |
| PC-24309 |
LFW273
Snail inhibitor
|
LFW273 is a specific, orally bioavailable small molecule inhibitor of zinc-finger transcription factor Snail with binding Kd of 1.7 uM, inhibits CREB-binding protein (CBP)-Snail interaction with Kd of 7.3 uM in MST assays. |
| PC-24033 |
EPS496
p300 inhibitor
|
EPS496 is a small molecule inhibitor of histone acetyltransferase p300, binds effectively to p300 and inhibits p300 kinase activation. |
| PC-23724 |
CHI-KAT8i5
KAT8 inhibitor
|
CHI-KAT8i5 is a specific small molecule inhibitor of KAT8 (lysine acetyltransferase 8), directly binds to KAT8 with SPR KD of 19.72 uM, suppresses esophageal squamous cell carcinoma (ESCC) growth through targeting KAT8/c-Myc signaling pathway. |
| PC-21843 |
SGF29 inhibitor DC60
SGF29 inhibitor
|
SGF29 inhibitor DC60 is a small molecule inhibitor of Spt-Ada-Gcn5 acetyltransferase (SAGA)-associated factor 29 (SGF29, CCDC101) with IC50 of 6.4 uM, binds to SGF29 second Tudor domain (SGF29 Tudor 2) and blocks SGF29 chromatin binding domain. |
| PC-20867 |
MG149
Tip60 (KAT5) inhibitor
|
MG149 is a selective histone acetyltransferase Tip60 (KAT5) inhibitor with IC50 of 74 uM, with no activity against PCAF and p300. |