| Cat. No. |
Product Name |
Information |
| PC-72238 |
NU9056
Tip60 (KAT5) inhibitor
|
NU9056 (NU 9056) is a specific Tip60 (KAT5) histone acetyltransferase inhibitor with IC50 of <2 uM. |
| PC-72165 |
CPI-1612
EP300/CBP inhibitor
|
CPI-1612 (CPI 1612) is a highly potent, selective, orally bioavailable EP300/CBP histone acetyltransferase inhibitor with IC50 of 8.1 nM (EP300 HAT SPA). |
| PC-38289 |
WM-3835
KAT7 inhibitor
|
WM-3835 (WM 3835) is a potent, high-specific, cell-permeable inhibitor of MYST acetyltransferase HBO1 (KAT7 or MYST2). |
| PC-38126 |
CCS1477
p300/CBP inhibitor
|
CCS1477 (Inobrodib) is an orally bioavailable, potent, and selective inhibitor of the p300/CBP bromodomain, binds to p300 and CBP with Kds of 1.3 and 1.7 nM respectively. |
| PC-36166 |
TTK21
CBP/p300 inhibitor
|
TTK21 (CBP-p300 activator TTK21) is a small molecule activator of CBP/p300 histone acetyltransferase activity with a maximal effect at a concentration of 275 uM. |
| PC-35580 |
WM-1119
KAT6A inhibitor
|
WM-1119 (WM1119) is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with Kd of 2 nM, shows greate bioavailability and specificity for KAT6A than WM-8014. |
| PC-35579 |
WM-8014
KAT6A inhibitor
|
WM-8014 (WM8014) is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with Kd of 5 nM and IC50 of 8 nM. |
| PC-35322 |
CPTH2
GCN5 inhibitor
|
CPTH2 is a specific histone acetyltransferase inhibitor modulating Gcn5 network in vitro and in vivo, inhibits H3 acetylation and induces cell-cycle perturbation and apoptosis in U-937 cells. |
| PC-35321 |
CPTH6 hydrobromide
GCN5/PCAF inhibitor
|
CPTH6 hydrobromide is a thiazole derivative that can reduce histone acetylation and histone acetyltransferase (HAT) activity in human leukemia cells, CPTH6 is a specific Gcn5/pCAF inhibitor. |
| PC-35320 |
CPTH6
GCN5/PCAF inhibitor
|
CPTH6 is a thiazole derivative that can reduce histone acetylation and histone acetyltransferase (HAT) activity in human leukemia cells, CPTH6 is a specific Gcn5/pCAF inhibitor. |
| PC-35191 |
MC2884
HAT/EZH2 inhibitor
|
MC2884 is a novel hybrid, dual HAT/EZH2 inhibitor with IC50 of 3.27, 8.35 and 4.56 uM for CBP, KAT5 and p300, respectively. |
| PC-63458 |
Remodelin Fluor
NAT10 inhibitor
|
Remodelin Fluor is a small molecule analog of Remodelin, demonstrates in vivo activitiy against NAT10, significantly enhances the healthspan in a Lmna G609G HGPS mouse model.. |
