Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : MC2884
Catalog No.: PC-35191Not For Human Use, Lab Use Only.
MC2884 is a novel hybrid, dual HAT/EZH2 inhibitor with IC50 of 3.27, 8.35 and 4.56 uM for CBP, KAT5 and p300, respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
MC2884 is a novel hybrid, dual HAT/EZH2 inhibitor with IC50 of 3.27, 8.35 and 4.56 uM for CBP, KAT5 and p300, respectively.
MC2884 induces caspase- and mitochondrial-dependent cancer-selective apoptosis on a variety of cancers, accompanied by ROS production.
MC2884 displays anticancer action in both hematological and solid cancer in vivo models, induces apoptosis in aggressive cancers and in primary leukemic blasts, also synergizes with BCL2 inhibitors.
| M.Wt | 523.268 | |
| Formula | C26H21Br2NO | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Petraglia F, et al. Oncotarget. 2018 May 22;9(39):25630-25646.
2. Singh AA, et al. Oncotarget. 2018 May 22;9(39):25647-25660.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
